QUIMERA SINTÉTICA MULTIEPITÓPICA COMO VACINA E TRATAMENTO CONTRA LEISHMANIOSE EM MAMÍFEROS

QUIMERA SINTÉTICA MULTIEPITÓPICA COMO VACINA E TRATAMENTO CONTRA LEISHMANIOSE EM MAMÍFEROS. Presenta invenção que se refere a quimeras sintéticas que incluem 4 peptídeos multiepitópicos contra Leishmania. Cada um dos peptídeos selecionado de uma proteína de Leishmania infantum. Elas são histonas nuc...

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Hauptverfasser: ORDEN GUTIÉRREZ, JOSÉ ANTONIO, MARTÍNEZ RODRIGO, ABEL, MAS ZUBIRI, ALICIA, CARRIÓN HERRERO, FRANCISCO JAVIER, DE LA FUENTE LÓPEZ, RICARDO, DOMÍNGUEZ BERNAL, GUSTAVO
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creator ORDEN GUTIÉRREZ, JOSÉ ANTONIO
MARTÍNEZ RODRIGO, ABEL
MAS ZUBIRI, ALICIA
CARRIÓN HERRERO, FRANCISCO JAVIER
DE LA FUENTE LÓPEZ, RICARDO
DOMÍNGUEZ BERNAL, GUSTAVO
description QUIMERA SINTÉTICA MULTIEPITÓPICA COMO VACINA E TRATAMENTO CONTRA LEISHMANIOSE EM MAMÍFEROS. Presenta invenção que se refere a quimeras sintéticas que incluem 4 peptídeos multiepitópicos contra Leishmania. Cada um dos peptídeos selecionado de uma proteína de Leishmania infantum. Elas são histonas nucleossomais H2A, H2B, H3 e H4. A invenção também se refere a uma composição farmacêutica que inclui a quimera sintética. Além disso, ela também se refere a uma vacina profilática e/ou terapêutica contra Leishmania spp. para seu uso em mamíferos e, especialmente, em humanos e em cães. Synthetic chimera which includes four multi-epitope peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are nucleosomal histones H2A, H2B, H3 and H4. The invention also relates to a pharmaceutical composition which includes the synthetic chimera. It also concerns a prophylactic and/or therapeutic vaccine against Leishmania spp. for use in mammals and especially in humans and dogs.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title QUIMERA SINTÉTICA MULTIEPITÓPICA COMO VACINA E TRATAMENTO CONTRA LEISHMANIOSE EM MAMÍFEROS
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