Derivados de rapamicina
a presente invenção refere-se a derivados de 32-deoxo-rapamicina de fórmula (i) (i), ou um sal farmaceuticamente aceitável dos mesmos, composições farmacêuticas e combinações farmacêuticas que compreendem um composto de fórmula (i) e a métodos de produção dos mesmos. no presente documento, também sã...
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| creator | BONAZZI SIMONE ROGGO SILVIO ANDREW W. PATTERSON SHAVLAKADZE TEA DAVID J. GLASS MIHALIC MANUEL ZUEGER PATRIK CONNOLLY MICHAEL |
| description | a presente invenção refere-se a derivados de 32-deoxo-rapamicina de fórmula (i) (i), ou um sal farmaceuticamente aceitável dos mesmos, composições farmacêuticas e combinações farmacêuticas que compreendem um composto de fórmula (i) e a métodos de produção dos mesmos. no presente documento, também são fornecidos métodos de uso de um composto de fórmula (i), ou de um sal farmaceuticamente aceitável do mesmo, para tratar as doenças e distúrbios descritos no presente documento.
The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein. |
| format | Patent |
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The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein.</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211116&DB=EPODOC&CC=BR&NR=112021011325A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211116&DB=EPODOC&CC=BR&NR=112021011325A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BONAZZI SIMONE</creatorcontrib><creatorcontrib>ROGGO SILVIO</creatorcontrib><creatorcontrib>ANDREW W. PATTERSON</creatorcontrib><creatorcontrib>SHAVLAKADZE TEA</creatorcontrib><creatorcontrib>DAVID J. GLASS</creatorcontrib><creatorcontrib>MIHALIC MANUEL</creatorcontrib><creatorcontrib>ZUEGER PATRIK</creatorcontrib><creatorcontrib>CONNOLLY MICHAEL</creatorcontrib><title>Derivados de rapamicina</title><description>a presente invenção refere-se a derivados de 32-deoxo-rapamicina de fórmula (i) (i), ou um sal farmaceuticamente aceitável dos mesmos, composições farmacêuticas e combinações farmacêuticas que compreendem um composto de fórmula (i) e a métodos de produção dos mesmos. no presente documento, também são fornecidos métodos de uso de um composto de fórmula (i), ou de um sal farmaceuticamente aceitável do mesmo, para tratar as doenças e distúrbios descritos no presente documento.
The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB3SS3KLEtMyS9WSElVKEosSMzNTM7MS-RhYE1LzClO5YXS3Ayqbq4hzh66qQX58anFBYnJqXmpJfFOQYaGRgZGhgaGhsZGpo5GxsSqAwDAriM1</recordid><startdate>20211116</startdate><enddate>20211116</enddate><creator>BONAZZI SIMONE</creator><creator>ROGGO SILVIO</creator><creator>ANDREW W. PATTERSON</creator><creator>SHAVLAKADZE TEA</creator><creator>DAVID J. GLASS</creator><creator>MIHALIC MANUEL</creator><creator>ZUEGER PATRIK</creator><creator>CONNOLLY MICHAEL</creator><scope>EVB</scope></search><sort><creationdate>20211116</creationdate><title>Derivados de rapamicina</title><author>BONAZZI SIMONE ; ROGGO SILVIO ; ANDREW W. PATTERSON ; SHAVLAKADZE TEA ; DAVID J. GLASS ; MIHALIC MANUEL ; ZUEGER PATRIK ; CONNOLLY MICHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR112021011325A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BONAZZI SIMONE</creatorcontrib><creatorcontrib>ROGGO SILVIO</creatorcontrib><creatorcontrib>ANDREW W. PATTERSON</creatorcontrib><creatorcontrib>SHAVLAKADZE TEA</creatorcontrib><creatorcontrib>DAVID J. GLASS</creatorcontrib><creatorcontrib>MIHALIC MANUEL</creatorcontrib><creatorcontrib>ZUEGER PATRIK</creatorcontrib><creatorcontrib>CONNOLLY MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BONAZZI SIMONE</au><au>ROGGO SILVIO</au><au>ANDREW W. PATTERSON</au><au>SHAVLAKADZE TEA</au><au>DAVID J. GLASS</au><au>MIHALIC MANUEL</au><au>ZUEGER PATRIK</au><au>CONNOLLY MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Derivados de rapamicina</title><date>2021-11-16</date><risdate>2021</risdate><abstract>a presente invenção refere-se a derivados de 32-deoxo-rapamicina de fórmula (i) (i), ou um sal farmaceuticamente aceitável dos mesmos, composições farmacêuticas e combinações farmacêuticas que compreendem um composto de fórmula (i) e a métodos de produção dos mesmos. no presente documento, também são fornecidos métodos de uso de um composto de fórmula (i), ou de um sal farmaceuticamente aceitável do mesmo, para tratar as doenças e distúrbios descritos no presente documento.
The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Derivados de rapamicina |
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