composições e métodos para degradação de proteína seletiva
trata-se de composições incluindo um polipeptídeo de fusão e métodos para produzir um polipeptídeo de fusão que inclui um polipeptídeo de ligação a cof1/crbn, polipeptídeo de ligação a cof2/crbn ou polipeptídeo de ligação a cof3/crbn e um polipeptídeo heterólogo de interesse. The invention provides...
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| creator | CARLA PATRICIA PINTO GUIMARAES CARLETON PROCTOR GOOLD MARC HORST PETER HILD NATHAN THOMAS ROSS JONATHAN M. SOLOMON SETH CARBONNEAU GREGORY MOTZ ROHAN ERIC JOHN BECKWITH ANDREI GOLOSOV JAMES E. BRADNER |
| description | trata-se de composições incluindo um polipeptídeo de fusão e métodos para produzir um polipeptídeo de fusão que inclui um polipeptídeo de ligação a cof1/crbn, polipeptídeo de ligação a cof2/crbn ou polipeptídeo de ligação a cof3/crbn e um polipeptídeo heterólogo de interesse.
The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest. |
| format | Patent |
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The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.</description><language>por</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200924&DB=EPODOC&CC=BR&NR=112020007576A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200924&DB=EPODOC&CC=BR&NR=112020007576A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CARLA PATRICIA PINTO GUIMARAES</creatorcontrib><creatorcontrib>CARLETON PROCTOR GOOLD</creatorcontrib><creatorcontrib>MARC HORST PETER HILD</creatorcontrib><creatorcontrib>NATHAN THOMAS ROSS</creatorcontrib><creatorcontrib>JONATHAN M. SOLOMON</creatorcontrib><creatorcontrib>SETH CARBONNEAU</creatorcontrib><creatorcontrib>GREGORY MOTZ</creatorcontrib><creatorcontrib>ROHAN ERIC JOHN BECKWITH</creatorcontrib><creatorcontrib>ANDREI GOLOSOV</creatorcontrib><creatorcontrib>JAMES E. BRADNER</creatorcontrib><title>composições e métodos para degradação de proteína seletiva</title><description>trata-se de composições incluindo um polipeptídeo de fusão e métodos para produzir um polipeptídeo de fusão que inclui um polipeptídeo de ligação a cof1/crbn, polipeptídeo de ligação a cof2/crbn ou polipeptídeo de ligação a cof3/crbn e um polipeptídeo heterólogo de interesse.
The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBIzs8tyC_OPLz88NbUYoVUhdzDK0vyU_KLFQoSixIVUlLTixJTEoGyi_OBHIWCovyS1MNr8xIVilNzUksyyxJ5GFjTEnOKU3mhNDeDqptriLOHbmpBfnxqcUFicmpeakm8U5ChoZGBkYGBgbmpuZmjkTGx6gBuiTbs</recordid><startdate>20200924</startdate><enddate>20200924</enddate><creator>CARLA PATRICIA PINTO GUIMARAES</creator><creator>CARLETON PROCTOR GOOLD</creator><creator>MARC HORST PETER HILD</creator><creator>NATHAN THOMAS ROSS</creator><creator>JONATHAN M. SOLOMON</creator><creator>SETH CARBONNEAU</creator><creator>GREGORY MOTZ</creator><creator>ROHAN ERIC JOHN BECKWITH</creator><creator>ANDREI GOLOSOV</creator><creator>JAMES E. BRADNER</creator><scope>EVB</scope></search><sort><creationdate>20200924</creationdate><title>composições e métodos para degradação de proteína seletiva</title><author>CARLA PATRICIA PINTO GUIMARAES ; CARLETON PROCTOR GOOLD ; MARC HORST PETER HILD ; NATHAN THOMAS ROSS ; JONATHAN M. SOLOMON ; SETH CARBONNEAU ; GREGORY MOTZ ; ROHAN ERIC JOHN BECKWITH ; ANDREI GOLOSOV ; JAMES E. BRADNER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR112020007576A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CARLA PATRICIA PINTO GUIMARAES</creatorcontrib><creatorcontrib>CARLETON PROCTOR GOOLD</creatorcontrib><creatorcontrib>MARC HORST PETER HILD</creatorcontrib><creatorcontrib>NATHAN THOMAS ROSS</creatorcontrib><creatorcontrib>JONATHAN M. SOLOMON</creatorcontrib><creatorcontrib>SETH CARBONNEAU</creatorcontrib><creatorcontrib>GREGORY MOTZ</creatorcontrib><creatorcontrib>ROHAN ERIC JOHN BECKWITH</creatorcontrib><creatorcontrib>ANDREI GOLOSOV</creatorcontrib><creatorcontrib>JAMES E. BRADNER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CARLA PATRICIA PINTO GUIMARAES</au><au>CARLETON PROCTOR GOOLD</au><au>MARC HORST PETER HILD</au><au>NATHAN THOMAS ROSS</au><au>JONATHAN M. SOLOMON</au><au>SETH CARBONNEAU</au><au>GREGORY MOTZ</au><au>ROHAN ERIC JOHN BECKWITH</au><au>ANDREI GOLOSOV</au><au>JAMES E. BRADNER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>composições e métodos para degradação de proteína seletiva</title><date>2020-09-24</date><risdate>2020</risdate><abstract>trata-se de composições incluindo um polipeptídeo de fusão e métodos para produzir um polipeptídeo de fusão que inclui um polipeptídeo de ligação a cof1/crbn, polipeptídeo de ligação a cof2/crbn ou polipeptídeo de ligação a cof3/crbn e um polipeptídeo heterólogo de interesse.
The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | composições e métodos para degradação de proteína seletiva |
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