3-amino piridinas como agonistas de gpbari
3-amino piridinas como agonistas de gpbari esta invenção refere-se a novas 3-aminopiridinas da fórmula (i) i em que b1, b2 e r1 até r6 são tais como definidos na descrição e nas reivindicações, bem como os seus sais farmaceuticamente aceitáveis. estes compostos são agonistas de gpbari e podem ser us...
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| creator | KYUNGJIN KIM HANS RICHTER PATRIZIO MATTEI PRABHA SABA KARNACHI SHERRIE LYNN PIETRANICO-COLE ULRIKE OBST CATERINA BISSANTZ HENRIETTA DEHMLOW RAINER E. MARTIN SHAWN DAVID ERICKSON CHRISTOPH ULLMER |
| description | 3-amino piridinas como agonistas de gpbari esta invenção refere-se a novas 3-aminopiridinas da fórmula (i) i em que b1, b2 e r1 até r6 são tais como definidos na descrição e nas reivindicações, bem como os seus sais farmaceuticamente aceitáveis. estes compostos são agonistas de gpbari e podem ser usados como medicamentos para o tratamento de enfermidades tais como diabetes do tipo ii.
This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes. |
| format | Patent |
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This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200825&DB=EPODOC&CC=BR&NR=112013022110A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200825&DB=EPODOC&CC=BR&NR=112013022110A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KYUNGJIN KIM</creatorcontrib><creatorcontrib>HANS RICHTER</creatorcontrib><creatorcontrib>PATRIZIO MATTEI</creatorcontrib><creatorcontrib>PRABHA SABA KARNACHI</creatorcontrib><creatorcontrib>SHERRIE LYNN PIETRANICO-COLE</creatorcontrib><creatorcontrib>ULRIKE OBST</creatorcontrib><creatorcontrib>CATERINA BISSANTZ</creatorcontrib><creatorcontrib>HENRIETTA DEHMLOW</creatorcontrib><creatorcontrib>RAINER E. MARTIN</creatorcontrib><creatorcontrib>SHAWN DAVID ERICKSON</creatorcontrib><creatorcontrib>CHRISTOPH ULLMER</creatorcontrib><title>3-amino piridinas como agonistas de gpbari</title><description>3-amino piridinas como agonistas de gpbari esta invenção refere-se a novas 3-aminopiridinas da fórmula (i) i em que b1, b2 e r1 até r6 são tais como definidos na descrição e nas reivindicações, bem como os seus sais farmaceuticamente aceitáveis. estes compostos são agonistas de gpbari e podem ser usados como medicamentos para o tratamento de enfermidades tais como diabetes do tipo ii.
This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAy1k3MzczLVyjILMpMycxLLFZIzs_NV0hMz8_LLC4BclNSFdILkhKLMnkYWNMSc4pTeaE0N4Oqm2uIs4duakF-fGpxQWJyal5qSbxTkKGhkYGhsYGRkaGhgaORMbHqADrSKgs</recordid><startdate>20200825</startdate><enddate>20200825</enddate><creator>KYUNGJIN KIM</creator><creator>HANS RICHTER</creator><creator>PATRIZIO MATTEI</creator><creator>PRABHA SABA KARNACHI</creator><creator>SHERRIE LYNN PIETRANICO-COLE</creator><creator>ULRIKE OBST</creator><creator>CATERINA BISSANTZ</creator><creator>HENRIETTA DEHMLOW</creator><creator>RAINER E. MARTIN</creator><creator>SHAWN DAVID ERICKSON</creator><creator>CHRISTOPH ULLMER</creator><scope>EVB</scope></search><sort><creationdate>20200825</creationdate><title>3-amino piridinas como agonistas de gpbari</title><author>KYUNGJIN KIM ; HANS RICHTER ; PATRIZIO MATTEI ; PRABHA SABA KARNACHI ; SHERRIE LYNN PIETRANICO-COLE ; ULRIKE OBST ; CATERINA BISSANTZ ; HENRIETTA DEHMLOW ; RAINER E. MARTIN ; SHAWN DAVID ERICKSON ; CHRISTOPH ULLMER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR112013022110A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KYUNGJIN KIM</creatorcontrib><creatorcontrib>HANS RICHTER</creatorcontrib><creatorcontrib>PATRIZIO MATTEI</creatorcontrib><creatorcontrib>PRABHA SABA KARNACHI</creatorcontrib><creatorcontrib>SHERRIE LYNN PIETRANICO-COLE</creatorcontrib><creatorcontrib>ULRIKE OBST</creatorcontrib><creatorcontrib>CATERINA BISSANTZ</creatorcontrib><creatorcontrib>HENRIETTA DEHMLOW</creatorcontrib><creatorcontrib>RAINER E. MARTIN</creatorcontrib><creatorcontrib>SHAWN DAVID ERICKSON</creatorcontrib><creatorcontrib>CHRISTOPH ULLMER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KYUNGJIN KIM</au><au>HANS RICHTER</au><au>PATRIZIO MATTEI</au><au>PRABHA SABA KARNACHI</au><au>SHERRIE LYNN PIETRANICO-COLE</au><au>ULRIKE OBST</au><au>CATERINA BISSANTZ</au><au>HENRIETTA DEHMLOW</au><au>RAINER E. MARTIN</au><au>SHAWN DAVID ERICKSON</au><au>CHRISTOPH ULLMER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-amino piridinas como agonistas de gpbari</title><date>2020-08-25</date><risdate>2020</risdate><abstract>3-amino piridinas como agonistas de gpbari esta invenção refere-se a novas 3-aminopiridinas da fórmula (i) i em que b1, b2 e r1 até r6 são tais como definidos na descrição e nas reivindicações, bem como os seus sais farmaceuticamente aceitáveis. estes compostos são agonistas de gpbari e podem ser usados como medicamentos para o tratamento de enfermidades tais como diabetes do tipo ii.
This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | 3-amino piridinas como agonistas de gpbari |
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