processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina
Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2-CH2Hal(II), with a benzylamine compound of the formula (III) in the presence of an acid scaveng...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | por |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NORBERT LUI THOMAS NORBERT MÜLLER GÜNTER SCHLEGEL JENS-DIETMAR HEINRICH CHRISTIAN FUNKE |
| description | Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2-CH2Hal(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_BR112013011410B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>BR112013011410B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_BR112013011410B13</originalsourceid><addsrcrecordid>eNrjZIgrKMpPTi0uzlcoSCxKVEhUKChKBbEOLz-8OF8hJVXBSMdIQVchJTMtpzS_KD-1JDMnMTczD6wysagkswikpjRXITk_tyC_uASsJSk1rwqqjIeBNS0xpziVF0pzM6i6uYY4e-imFuTHpxYXJCan5qWWxDsFGRoaGRgaGxgamhgaOBkaE6sOAC-zPhU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina</title><source>esp@cenet</source><creator>NORBERT LUI ; THOMAS NORBERT MÜLLER ; GÜNTER SCHLEGEL ; JENS-DIETMAR HEINRICH ; CHRISTIAN FUNKE</creator><creatorcontrib>NORBERT LUI ; THOMAS NORBERT MÜLLER ; GÜNTER SCHLEGEL ; JENS-DIETMAR HEINRICH ; CHRISTIAN FUNKE</creatorcontrib><description>Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2-CH2Hal(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.</description><language>por</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181211&DB=EPODOC&CC=BR&NR=112013011410B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181211&DB=EPODOC&CC=BR&NR=112013011410B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NORBERT LUI</creatorcontrib><creatorcontrib>THOMAS NORBERT MÜLLER</creatorcontrib><creatorcontrib>GÜNTER SCHLEGEL</creatorcontrib><creatorcontrib>JENS-DIETMAR HEINRICH</creatorcontrib><creatorcontrib>CHRISTIAN FUNKE</creatorcontrib><title>processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina</title><description>Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2-CH2Hal(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgrKMpPTi0uzlcoSCxKVEhUKChKBbEOLz-8OF8hJVXBSMdIQVchJTMtpzS_KD-1JDMnMTczD6wysagkswikpjRXITk_tyC_uASsJSk1rwqqjIeBNS0xpziVF0pzM6i6uYY4e-imFuTHpxYXJCan5qWWxDsFGRoaGRgaGxgamhgaOBkaE6sOAC-zPhU</recordid><startdate>20181211</startdate><enddate>20181211</enddate><creator>NORBERT LUI</creator><creator>THOMAS NORBERT MÜLLER</creator><creator>GÜNTER SCHLEGEL</creator><creator>JENS-DIETMAR HEINRICH</creator><creator>CHRISTIAN FUNKE</creator><scope>EVB</scope></search><sort><creationdate>20181211</creationdate><title>processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina</title><author>NORBERT LUI ; THOMAS NORBERT MÜLLER ; GÜNTER SCHLEGEL ; JENS-DIETMAR HEINRICH ; CHRISTIAN FUNKE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR112013011410B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2018</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>NORBERT LUI</creatorcontrib><creatorcontrib>THOMAS NORBERT MÜLLER</creatorcontrib><creatorcontrib>GÜNTER SCHLEGEL</creatorcontrib><creatorcontrib>JENS-DIETMAR HEINRICH</creatorcontrib><creatorcontrib>CHRISTIAN FUNKE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NORBERT LUI</au><au>THOMAS NORBERT MÜLLER</au><au>GÜNTER SCHLEGEL</au><au>JENS-DIETMAR HEINRICH</au><au>CHRISTIAN FUNKE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina</title><date>2018-12-11</date><risdate>2018</risdate><abstract>Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2-CH2Hal(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | por |
| recordid | cdi_epo_espacenet_BR112013011410B1 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY |
| title | processo para a preparação de 2,2 - difluoroetilamina a partir de um composto de benzilamina |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T09%3A20%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NORBERT%20LUI&rft.date=2018-12-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EBR112013011410B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |