Produção de propanóis álcoois e polióis em organismos de bioprocessamento consolidados

The present invention provides for novel metabolic pathways leading to propanol, alcohol or polyol formation in a consolidated bioprocessing system (CBP), where lignocellulosic biomass is efficiently converted to such products. More specifically, the invention provides for a recombinant microorganis...

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Hauptverfasser: IV, VINEET RAJGARHIA, SHITAL A. TRIPATHI, ALLAN FROEHLICH, ELENA BREVNOVA, JOHN MCBRIDE, HANS VAN DIJKEN, ARTHUR J. SHAW, WILLIAM RYAN SILLERS, JIM FLATT, NICHY CAIAZZA
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creator IV
VINEET RAJGARHIA
SHITAL A. TRIPATHI
ALLAN FROEHLICH
ELENA BREVNOVA
JOHN MCBRIDE
HANS VAN DIJKEN
ARTHUR J. SHAW
WILLIAM RYAN SILLERS
JIM FLATT
NICHY CAIAZZA
description The present invention provides for novel metabolic pathways leading to propanol, alcohol or polyol formation in a consolidated bioprocessing system (CBP), where lignocellulosic biomass is efficiently converted to such products. More specifically, the invention provides for a recombinant microorganism, where the microorganism expresses one or more native and/or heterologous enzymes; where the one or more enzymes function in one or more engineered metabolic pathways to achieve: (1) conversion of a carbohydrate source to 1,2-propanediol, isopropropanol, ethanol and/or glycerol; (2) conversion of a carbohydrate source to n-propanol and isopropanol; (3) conversion of a carbohydrate source to isopropanol and methanol; or (4) conversion of a carbohydrate source to propanediol and acetone; wherein the one or more native and/or heterologous enzymes is activated, upregulated or downregulated.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Produção de propanóis álcoois e polióis em organismos de bioprocessamento consolidados
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