l-asparaginase recombinante de zymomonas

l-asparaginase recombinante de zymomonas. a presente invenção relata a construção e otimização de genes sintéticos a partir do gene de l-asparaginase de zymomonas mobilis, sua clonagem e expressão em escherichia coli. a obtenção de tal enzima tem por objetivo produzir altos níveis de uma nova l-aspa...

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Hauptverfasser:	TITO LIVIO MOITINHO ALVES, KAREN EINSFELDT
Format:	Patent
Sprache:	por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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creator	TITO LIVIO MOITINHO ALVES KAREN EINSFELDT
description	l-asparaginase recombinante de zymomonas. a presente invenção relata a construção e otimização de genes sintéticos a partir do gene de l-asparaginase de zymomonas mobilis, sua clonagem e expressão em escherichia coli. a obtenção de tal enzima tem por objetivo produzir altos níveis de uma nova l-asparaginase para uso em composições farmacêuticas a base de l-asparaginase a serem utilizadas. no tratamento de câncer, tumores, doenças com proliferação celular, assim como outras aplicações médicas. The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning same and expression thereof in Escherichia coli. The purpose of the production of said enzyme is for producing high levels of a novel L-asparaginase that can be used in L-asparaginase-based pharmaceutical compositions for treating cancer, tumours and diseases involving cell proliferation, as well as for other medical applications.
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The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning same and expression thereof in Escherichia coli. The purpose of the production of said enzyme is for producing high levels of a novel L-asparaginase that can be used in L-asparaginase-based pharmaceutical compositions for treating cancer, tumours and diseases involving cell proliferation, as well as for other medical applications.</description><language>por</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160315&DB=EPODOC&CC=BR&NR=102014000585A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160315&DB=EPODOC&CC=BR&NR=102014000585A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TITO LIVIO MOITINHO ALVES</creatorcontrib><creatorcontrib>KAREN EINSFELDT</creatorcontrib><title>l-asparaginase recombinante de zymomonas</title><description>l-asparaginase recombinante de zymomonas. a presente invenção relata a construção e otimização de genes sintéticos a partir do gene de l-asparaginase de zymomonas mobilis, sua clonagem e expressão em escherichia coli. a obtenção de tal enzima tem por objetivo produzir altos níveis de uma nova l-asparaginase para uso em composições farmacêuticas a base de l-asparaginase a serem utilizadas. no tratamento de câncer, tumores, doenças com proliferação celular, assim como outras aplicações médicas. The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning same and expression thereof in Escherichia coli. The purpose of the production of said enzyme is for producing high levels of a novel L-asparaginase that can be used in L-asparaginase-based pharmaceutical compositions for treating cancer, tumours and diseases involving cell proliferation, as well as for other medical applications.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDI0U0sLkgsSkzPzEssTlUoSk3Oz00CsvNKUhVSUhWqKnPzc_OBUjwMrGmJOcWpvFCam0HVzTXE2UM3tSA_PhVoRHJqXmpJvFOQoYGRgaGJgYGBqYWpo5ExseoAMg0qKg</recordid><startdate>20160315</startdate><enddate>20160315</enddate><creator>TITO LIVIO MOITINHO ALVES</creator><creator>KAREN EINSFELDT</creator><scope>EVB</scope></search><sort><creationdate>20160315</creationdate><title>l-asparaginase recombinante de zymomonas</title><author>TITO LIVIO MOITINHO ALVES ; KAREN EINSFELDT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR102014000585A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2016</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>TITO LIVIO MOITINHO ALVES</creatorcontrib><creatorcontrib>KAREN EINSFELDT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TITO LIVIO MOITINHO ALVES</au><au>KAREN EINSFELDT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>l-asparaginase recombinante de zymomonas</title><date>2016-03-15</date><risdate>2016</risdate><abstract>l-asparaginase recombinante de zymomonas. a presente invenção relata a construção e otimização de genes sintéticos a partir do gene de l-asparaginase de zymomonas mobilis, sua clonagem e expressão em escherichia coli. a obtenção de tal enzima tem por objetivo produzir altos níveis de uma nova l-asparaginase para uso em composições farmacêuticas a base de l-asparaginase a serem utilizadas. no tratamento de câncer, tumores, doenças com proliferação celular, assim como outras aplicações médicas. The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning same and expression thereof in Escherichia coli. The purpose of the production of said enzyme is for producing high levels of a novel L-asparaginase that can be used in L-asparaginase-based pharmaceutical compositions for treating cancer, tumours and diseases involving cell proliferation, as well as for other medical applications.</abstract><oa>free_for_read</oa></addata></record>
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subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
title	l-asparaginase recombinante de zymomonas
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