Processo de preparação de rosuvastatina

"PROCESSO DE PREPARAçãO DE ROSUVASTATINA". A presente invenção se refere a um processo, industrialmente vantajoso e eficaz sob o ponto de vista de custos, para a preparação de 4-4(fluorfenil)-6-isopropil-2-(N-metil-N-metilsulfonilamino)-5-pirimidinoc arboxaldeído, aqui referido como pirimi...

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Hauptverfasser: SWARGAM SATHYANARAYANA, SHANTANU DE, HASHIM NIZAR POOVANATHIL NAGOOR MEERAN, MOHAMMAD RAFEEQ, YATENDRA KUMAR
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creator SWARGAM SATHYANARAYANA
SHANTANU DE
HASHIM NIZAR POOVANATHIL NAGOOR MEERAN
MOHAMMAD RAFEEQ
YATENDRA KUMAR
description "PROCESSO DE PREPARAçãO DE ROSUVASTATINA". A presente invenção se refere a um processo, industrialmente vantajoso e eficaz sob o ponto de vista de custos, para a preparação de 4-4(fluorfenil)-6-isopropil-2-(N-metil-N-metilsulfonilamino)-5-pirimidinoc arboxaldeído, aqui referido como pirimidino-aldeído de Fórmula estrutural I, e ao uso deste composto como intermediário para a preparação de rosuvastatina. The present invention relates to a cost effective and industrially advantageous process for the preparation of 4-4(fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)-5-pyrimidinecarboxaldehyde, referred to here as pyrimidine aldehyde of structural Formula I and to the use of this compound as intermediate for the preparation of rosuvastatin.
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The present invention relates to a cost effective and industrially advantageous process for the preparation of 4-4(fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)-5-pyrimidinecarboxaldehyde, referred to here as pyrimidine aldehyde of structural Formula I and to the use of this compound as intermediate for the preparation of rosuvastatin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAMKMpPTi0uzldISVUoKEotSCxKPLz88GIwvyi_uLQssbgksSQzL5GHgTUtMac4lRdKczPIu7mGOHvophbkx6cWFyQmp-allsQ7BRkYGxoaWpo6GhNWAQD-7SlY</recordid><startdate>20050222</startdate><enddate>20050222</enddate><creator>SWARGAM SATHYANARAYANA</creator><creator>SHANTANU DE</creator><creator>HASHIM NIZAR POOVANATHIL NAGOOR MEERAN</creator><creator>MOHAMMAD RAFEEQ</creator><creator>YATENDRA KUMAR</creator><scope>EVB</scope></search><sort><creationdate>20050222</creationdate><title>Processo de preparação de rosuvastatina</title><author>SWARGAM SATHYANARAYANA ; SHANTANU DE ; HASHIM NIZAR POOVANATHIL NAGOOR MEERAN ; MOHAMMAD RAFEEQ ; YATENDRA KUMAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BR0311195A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2005</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>SWARGAM SATHYANARAYANA</creatorcontrib><creatorcontrib>SHANTANU DE</creatorcontrib><creatorcontrib>HASHIM NIZAR POOVANATHIL NAGOOR MEERAN</creatorcontrib><creatorcontrib>MOHAMMAD RAFEEQ</creatorcontrib><creatorcontrib>YATENDRA KUMAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SWARGAM SATHYANARAYANA</au><au>SHANTANU DE</au><au>HASHIM NIZAR POOVANATHIL NAGOOR MEERAN</au><au>MOHAMMAD RAFEEQ</au><au>YATENDRA KUMAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Processo de preparação de rosuvastatina</title><date>2005-02-22</date><risdate>2005</risdate><abstract>"PROCESSO DE PREPARAçãO DE ROSUVASTATINA". 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Processo de preparação de rosuvastatina
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