CARBOXY DERIVATIVE OF PYROL AND PROCESS FOR ITS PREPARATION

This carboxylic derivative of pyrol is used as an intermediate in obtaining β-lactam antibiotics by means of N-acylation. It helps diversify the nature of antibacterial agents countering the increasing resistance to their effect. The product has the following formula:It is obtained by condensing eth...

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Hauptverfasser: BIZHEV, ATANAS T, PRODANOVA, PENKA P
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creator BIZHEV, ATANAS T
PRODANOVA, PENKA P
description This carboxylic derivative of pyrol is used as an intermediate in obtaining β-lactam antibiotics by means of N-acylation. It helps diversify the nature of antibacterial agents countering the increasing resistance to their effect. The product has the following formula:It is obtained by condensing ethyl-/Z/-2/methyloximino/-3-oxobutyrate with ω-aminoacetophenon and a subsequent saponification of the carbetoxy group into a carboxylic one.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title CARBOXY DERIVATIVE OF PYROL AND PROCESS FOR ITS PREPARATION
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