PROCEDE POUR LA PREPARATION DE MATIERES BIOCOMPATIBLES PAR L'IMMOBILISATION SUPERFICIELLE DE L'APYRASE, ET ARTICLES FABRIQUES OBTENUS PAR CE PROCEDE

A prosthetic polymer material is made non-thrombogenic by immobilizing apyrase on its surface. Immobilization is preferably carried out by hydrolytically activating the surface of a polyamide polymer or a polyethylene terphthalate polymer, and treating the hydrolyzed polymer with a solution of cross...

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Bibliographische Detailangaben
Hauptverfasser: W. MARCONI, F. PITTALIS, F. BARTOLI
Format: Patent
Sprache:fre
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Zusammenfassung:A prosthetic polymer material is made non-thrombogenic by immobilizing apyrase on its surface. Immobilization is preferably carried out by hydrolytically activating the surface of a polyamide polymer or a polyethylene terphthalate polymer, and treating the hydrolyzed polymer with a solution of cross-linking agent and a solution of apyrase. The apyrase converts adenosine diphosphate to adenosine monophosphate and adenosine whereby the formation of thrombi is inhibited.