DERIVES DE LA SECOERGOLINE

derivs. of formula (I) and their salts are new (where R1 = 1-4C alkyl, allyl or 2-phenylethyl, R2 = CH2R1 or CH2NHR2 or -COR3, R1 = H, halogen, OH, alkoxy, acyloxy, carbamoyl, substd. carbamoyl, carboxy ester, tosyloxy, mesyloxy, cyano, cyanomethyl, or substd. cyanomethyl, R2 = 1-4C alkyl, pyridyl,...

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Hauptverfasser: A. TEMPERILLI, L. BERNARDI
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creator A. TEMPERILLI
L. BERNARDI
description derivs. of formula (I) and their salts are new (where R1 = 1-4C alkyl, allyl or 2-phenylethyl, R2 = CH2R1 or CH2NHR2 or -COR3, R1 = H, halogen, OH, alkoxy, acyloxy, carbamoyl, substd. carbamoyl, carboxy ester, tosyloxy, mesyloxy, cyano, cyanomethyl, or substd. cyanomethyl, R2 = 1-4C alkyl, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl or thiazolyl, R3 = alkoxy or (substd)amino, R3 and R4 both = H or together form a double bond, R5 = H, or methyl. (I) used as alpha-adrenergic blocking agents, hypotensives, CNS depressants, antispasmodics, analgesics and antiprolactinic agents.
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BERNARDI</creatorcontrib><description>derivs. of formula (I) and their salts are new (where R1 = 1-4C alkyl, allyl or 2-phenylethyl, R2 = CH2R1 or CH2NHR2 or -COR3, R1 = H, halogen, OH, alkoxy, acyloxy, carbamoyl, substd. carbamoyl, carboxy ester, tosyloxy, mesyloxy, cyano, cyanomethyl, or substd. cyanomethyl, R2 = 1-4C alkyl, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl or thiazolyl, R3 = alkoxy or (substd)amino, R3 and R4 both = H or together form a double bond, R5 = H, or methyl. 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TEMPERILLI</creatorcontrib><creatorcontrib>L. BERNARDI</creatorcontrib><title>DERIVES DE LA SECOERGOLINE</title><description>derivs. of formula (I) and their salts are new (where R1 = 1-4C alkyl, allyl or 2-phenylethyl, R2 = CH2R1 or CH2NHR2 or -COR3, R1 = H, halogen, OH, alkoxy, acyloxy, carbamoyl, substd. carbamoyl, carboxy ester, tosyloxy, mesyloxy, cyano, cyanomethyl, or substd. cyanomethyl, R2 = 1-4C alkyl, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl or thiazolyl, R3 = alkoxy or (substd)amino, R3 and R4 both = H or together form a double bond, R5 = H, or methyl. (I) used as alpha-adrenergic blocking agents, hypotensives, CNS depressants, antispasmodics, analgesics and antiprolactinic agents.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1980</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBycQ3yDHMNVnBxVfBxVAh2dfZ3DXL39_H0c-VhYE1LzClO5YXS3Axybq4hzh66qQX58anFBYnJqXmpJfFOrhYWxkaWxo7GBBUAAGbfHtA</recordid><startdate>19800901</startdate><enddate>19800901</enddate><creator>A. TEMPERILLI</creator><creator>L. 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BERNARDI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>A. TEMPERILLI</au><au>L. BERNARDI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVES DE LA SECOERGOLINE</title><date>1980-09-01</date><risdate>1980</risdate><abstract>derivs. of formula (I) and their salts are new (where R1 = 1-4C alkyl, allyl or 2-phenylethyl, R2 = CH2R1 or CH2NHR2 or -COR3, R1 = H, halogen, OH, alkoxy, acyloxy, carbamoyl, substd. carbamoyl, carboxy ester, tosyloxy, mesyloxy, cyano, cyanomethyl, or substd. cyanomethyl, R2 = 1-4C alkyl, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl or thiazolyl, R3 = alkoxy or (substd)amino, R3 and R4 both = H or together form a double bond, R5 = H, or methyl. (I) used as alpha-adrenergic blocking agents, hypotensives, CNS depressants, antispasmodics, analgesics and antiprolactinic agents.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVES DE LA SECOERGOLINE
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