DIARYLBUTANOLAMINES ANTI-ARYTHMIQUES
A method of preparing diarylhydroxybutylamine compounds of the formula I **(See formula)** or R2 and R3 taken together with the adjacent nitrogen atom to which they are attached, complete a heterocyclic ring selected from methyl or substituted dimethyl pyrrolidine, piperidine, morpholine or pyrrolid...
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| creator | B.B. MOLLOY |
| description | A method of preparing diarylhydroxybutylamine compounds of the formula I **(See formula)** or R2 and R3 taken together with the adjacent nitrogen atom to which they are attached, complete a heterocyclic ring selected from methyl or substituted dimethyl pyrrolidine, piperidine, morpholine or pyrrolidine, piperidine and morpholine; and its pharmaceutically acceptable, non-toxic salts, characterized by reacting a 1,2-epoxy 4,4-diarylbutane compound of formula II **(See formula)** where X is as defined above, with at least one equivalent of an amine of the formula **(See formula)** where R2 and R3 are as defined above, at a temperature of between 50º and 180ºC. (Machine-translation by Google Translate, not legally binding) |
| format | Patent |
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MOLLOY</creatorcontrib><description>A method of preparing diarylhydroxybutylamine compounds of the formula I **(See formula)** or R2 and R3 taken together with the adjacent nitrogen atom to which they are attached, complete a heterocyclic ring selected from methyl or substituted dimethyl pyrrolidine, piperidine, morpholine or pyrrolidine, piperidine and morpholine; and its pharmaceutically acceptable, non-toxic salts, characterized by reacting a 1,2-epoxy 4,4-diarylbutane compound of formula II **(See formula)** where X is as defined above, with at least one equivalent of an amine of the formula **(See formula)** where R2 and R3 are as defined above, at a temperature of between 50º and 180ºC. (Machine-translation by Google Translate, not legally binding)</description><language>fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1976</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19761202&DB=EPODOC&CC=BE&NR=842484A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19761202&DB=EPODOC&CC=BE&NR=842484A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>B.B. MOLLOY</creatorcontrib><title>DIARYLBUTANOLAMINES ANTI-ARYTHMIQUES</title><description>A method of preparing diarylhydroxybutylamine compounds of the formula I **(See formula)** or R2 and R3 taken together with the adjacent nitrogen atom to which they are attached, complete a heterocyclic ring selected from methyl or substituted dimethyl pyrrolidine, piperidine, morpholine or pyrrolidine, piperidine and morpholine; and its pharmaceutically acceptable, non-toxic salts, characterized by reacting a 1,2-epoxy 4,4-diarylbutane compound of formula II **(See formula)** where X is as defined above, with at least one equivalent of an amine of the formula **(See formula)** where R2 and R3 are as defined above, at a temperature of between 50º and 180ºC. (Machine-translation by Google Translate, not legally binding)</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1976</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBx8XQMivRxCg1x9PP3cfT19HMNVnD0C_HUBQqHePh6Boa6BvMwsKYl5hSn8kJpbgY5N9cQZw_d1IL8-NTigsTk1LzUkngnVwsTIxMLE0djggoA5SkiOQ</recordid><startdate>19761202</startdate><enddate>19761202</enddate><creator>B.B. MOLLOY</creator><scope>EVB</scope></search><sort><creationdate>19761202</creationdate><title>DIARYLBUTANOLAMINES ANTI-ARYTHMIQUES</title><author>B.B. MOLLOY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BE842484A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fre</language><creationdate>1976</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>B.B. MOLLOY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>B.B. MOLLOY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIARYLBUTANOLAMINES ANTI-ARYTHMIQUES</title><date>1976-12-02</date><risdate>1976</risdate><abstract>A method of preparing diarylhydroxybutylamine compounds of the formula I **(See formula)** or R2 and R3 taken together with the adjacent nitrogen atom to which they are attached, complete a heterocyclic ring selected from methyl or substituted dimethyl pyrrolidine, piperidine, morpholine or pyrrolidine, piperidine and morpholine; and its pharmaceutically acceptable, non-toxic salts, characterized by reacting a 1,2-epoxy 4,4-diarylbutane compound of formula II **(See formula)** where X is as defined above, with at least one equivalent of an amine of the formula **(See formula)** where R2 and R3 are as defined above, at a temperature of between 50º and 180ºC. (Machine-translation by Google Translate, not legally binding)</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | DIARYLBUTANOLAMINES ANTI-ARYTHMIQUES |
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