1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters

1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters

Cpds (I): (where R is 1-8C alkyl; R1 is H or 1-6C alkyl; R2 is 1-8C alkyl, and R3 is H, F, Cl, br or 1-4C alkoxy provided R2 is not Me when R is Me and R1 and R3 are both H) are prepd by reacting a cpd (I) (where R is H or alkali metal and R1, R2 and R3 are as defined, or R2 is H or alkali metal and...

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1. Verfasser: G.E. HARDTMANN
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator G.E. HARDTMANN
description Cpds (I): (where R is 1-8C alkyl; R1 is H or 1-6C alkyl; R2 is 1-8C alkyl, and R3 is H, F, Cl, br or 1-4C alkoxy provided R2 is not Me when R is Me and R1 and R3 are both H) are prepd by reacting a cpd (I) (where R is H or alkali metal and R1, R2 and R3 are as defined, or R2 is H or alkali metal and R, R1 and R3 are as defined) with R6X (where R6 is 1-8C alkyl and X is Cl, Br I or OB; where B is MeSO2, PhSO2, or p-Me. C6H4SO2) or by reacting a cpd (IV) with (III) ot give (II) which is decarboxylated to give (I,R1=H) (where R4' is 1-8C alkyl; R9 is 1-4C alkyl; M is an alkali metal). Cpds (I) and (II) are used in the prepn of medicaments.
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HARDTMANN</creatorcontrib><description>Cpds (I): (where R is 1-8C alkyl; R1 is H or 1-6C alkyl; R2 is 1-8C alkyl, and R3 is H, F, Cl, br or 1-4C alkoxy provided R2 is not Me when R is Me and R1 and R3 are both H) are prepd by reacting a cpd (I) (where R is H or alkali metal and R1, R2 and R3 are as defined, or R2 is H or alkali metal and R, R1 and R3 are as defined) with R6X (where R6 is 1-8C alkyl and X is Cl, Br I or OB; where B is MeSO2, PhSO2, or p-Me. C6H4SO2) or by reacting a cpd (IV) with (III) ot give (II) which is decarboxylated to give (I,R1=H) (where R4' is 1-8C alkyl; R9 is 1-4C alkyl; M is an alkali metal). 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HARDTMANN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BE806848A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1974</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>G.E. HARDTMANN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>G.E. HARDTMANN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters</title><date>1974-04-30</date><risdate>1974</risdate><abstract>Cpds (I): (where R is 1-8C alkyl; R1 is H or 1-6C alkyl; R2 is 1-8C alkyl, and R3 is H, F, Cl, br or 1-4C alkoxy provided R2 is not Me when R is Me and R1 and R3 are both H) are prepd by reacting a cpd (I) (where R is H or alkali metal and R1, R2 and R3 are as defined, or R2 is H or alkali metal and R, R1 and R3 are as defined) with R6X (where R6 is 1-8C alkyl and X is Cl, Br I or OB; where B is MeSO2, PhSO2, or p-Me. C6H4SO2) or by reacting a cpd (IV) with (III) ot give (II) which is decarboxylated to give (I,R1=H) (where R4' is 1-8C alkyl; R9 is 1-4C alkyl; M is an alkali metal). Cpds (I) and (II) are used in the prepn of medicaments.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters
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