Nouveaux dérivés du thiazole et leur préparation
Substd 6,7-dihydro-and 2,36,7-tetrahydro-SH-thiazolo (3,2a)-pyrimidines and their salts. N3A. Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me o...
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creator | R.E. MANNING W.J. HOULIHAN |
description | Substd 6,7-dihydro-and 2,36,7-tetrahydro-SH-thiazolo (3,2a)-pyrimidines and their salts. N3A. Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me or Et, R3 = Cl, R2 = R4 = H, and n = 2., esp. those where A = H and B = OH. Used as (a) Anoretics and antidepressants (dose: 35-300 mg. (n=3); 15-150 mg. (n=2) and diuretics (n=z) Dose : 50-500 mg. Preparation is, e.g. as follows:- X = Br or Cl. |
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Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me or Et, R3 = Cl, R2 = R4 = H, and n = 2., esp. those where A = H and B = OH. Used as (a) Anoretics and antidepressants (dose: 35-300 mg. (n=3); 15-150 mg. (n=2) and diuretics (n=z) Dose : 50-500 mg. Preparation is, e.g. as follows:- X = Br or Cl.</description><language>fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1970</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19700129&DB=EPODOC&CC=BE&NR=736739A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19700129&DB=EPODOC&CC=BE&NR=736739A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>R.E. MANNING</creatorcontrib><creatorcontrib>W.J. HOULIHAN</creatorcontrib><title>Nouveaux dérivés du thiazole et leur préparation</title><description>Substd 6,7-dihydro-and 2,36,7-tetrahydro-SH-thiazolo (3,2a)-pyrimidines and their salts. N3A. Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me or Et, R3 = Cl, R2 = R4 = H, and n = 2., esp. those where A = H and B = OH. Used as (a) Anoretics and antidepressants (dose: 35-300 mg. (n=3); 15-150 mg. (n=2) and diuretics (n=z) Dose : 50-500 mg. Preparation is, e.g. as follows:- X = Br or Cl.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1970</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD2yy8tS00srVBIObyyKLPs8MpihZRShZKMzMSq_JxUhdQShZzU0iKFgqLDKwsSixJLMvPzeBhY0xJzilN5oTQ3g5yba4izh25qQX58anFBYnJqXmpJvJOrubGZubGlozFBBQD10i13</recordid><startdate>19700129</startdate><enddate>19700129</enddate><creator>R.E. MANNING</creator><creator>W.J. HOULIHAN</creator><scope>EVB</scope></search><sort><creationdate>19700129</creationdate><title>Nouveaux dérivés du thiazole et leur préparation</title><author>R.E. MANNING ; W.J. HOULIHAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BE736739A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fre</language><creationdate>1970</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>R.E. MANNING</creatorcontrib><creatorcontrib>W.J. HOULIHAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>R.E. MANNING</au><au>W.J. HOULIHAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Nouveaux dérivés du thiazole et leur préparation</title><date>1970-01-29</date><risdate>1970</risdate><abstract>Substd 6,7-dihydro-and 2,36,7-tetrahydro-SH-thiazolo (3,2a)-pyrimidines and their salts. N3A. Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me or Et, R3 = Cl, R2 = R4 = H, and n = 2., esp. those where A = H and B = OH. Used as (a) Anoretics and antidepressants (dose: 35-300 mg. (n=3); 15-150 mg. (n=2) and diuretics (n=z) Dose : 50-500 mg. Preparation is, e.g. as follows:- X = Br or Cl.</abstract><oa>free_for_read</oa></addata></record> |
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title | Nouveaux dérivés du thiazole et leur préparation |
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