Hydrogel-driven drug dosage form

Hydrogel-driven drug dosage form

A controlled -release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating arou...

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Hauptverfasser: DWAYNE THOMAS FRIESEN, LEAH ELIZABETH APPEL, MARK BRIAN CHIDLAW, KELLY LINCOLN SMITH, AVINASH GOVIND THOMBRE, WILLIAM JOHN CURATOLO, RONALD ARTHUR BEYERINCK
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator DWAYNE THOMAS FRIESEN
LEAH ELIZABETH APPEL
MARK BRIAN CHIDLAW
KELLY LINCOLN SMITH
AVINASH GOVIND THOMBRE
WILLIAM JOHN CURATOLO
RONALD ARTHUR BEYERINCK
description A controlled -release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Hydrogel-driven drug dosage form
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