Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens

Disclosed herein are methods and compositions for enhancing the immunogenicity of a preselected protein or peptide antigen in a mammal. Immunogenicity is enhanced by fusing the preselected antigen to an immunoglobulin heavy chain constant region to produce an Fc-antigen fusion protein. The Fc-antige...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIN MING LO, JOHN S. WESOLOWSKI JR, STEPHEN D. GILLIES
Format: Patent
Sprache:eng
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