Selective thyroid hormone analogs

Selective thyroid hormone agonists are disclosed that are highly selective for the TR beta subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.

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Hauptverfasser: HIKARI YOSHIHARA, GRAZIA CHELLINI, RALFF C. J. RIBEIRO, THOMAS S. SCANLAN, JOHN D BAXTER, JAMES APRILETTI
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creator HIKARI YOSHIHARA
GRAZIA CHELLINI
RALFF C. J. RIBEIRO
THOMAS S. SCANLAN
JOHN D BAXTER
JAMES APRILETTI
description Selective thyroid hormone agonists are disclosed that are highly selective for the TR beta subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Selective thyroid hormone analogs
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