Sigma receptor ligands and the use thereof

Sigma receptor ligands and the use thereof

PCT No. PCT/US94/07121 Sec. 371 Date Feb. 21, 1996 Sec. 102(e) Date Feb. 21, 1996 PCT Filed Jun. 23, 1994 PCT Pub. No. WO95/00131 PCT Pub. Date Jan. 5, 1995The invention relates to methods for the treatment of central nervous system disorders, neurological disorders, gastrointestinal disorders, drug...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JAMES B FISCHER, RICHARD A GLENNON
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:PCT No. PCT/US94/07121 Sec. 371 Date Feb. 21, 1996 Sec. 102(e) Date Feb. 21, 1996 PCT Filed Jun. 23, 1994 PCT Pub. No. WO95/00131 PCT Pub. Date Jan. 5, 1995The invention relates to methods for the treatment of central nervous system disorders, neurological disorders, gastrointestinal disorders, drug abuse, angina, migraine, hypertension and depression by administering a pharmaceutical composition comprising an effective amount of certain sigma receptor ligands to a patient in need of such treatment. The invention further relates to novel sigma receptor ligands having high binding to the sigma receptor and pharmaceutical compositions thereof.