Polymorphs of the prodrug 6-N-(L-ALA-L-ALA)-trovafloxacin

PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - P...

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Hauptverfasser:	TIMOTHY NORRIS, JAMES J. MCGARRY, DOUGLAS J.M. ALLEN
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Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	TIMOTHY NORRIS JAMES J. MCGARRY DOUGLAS J.M. ALLEN
description	PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.
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Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980910&DB=EPODOC&CC=AU&NR=696414B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980910&DB=EPODOC&CC=AU&NR=696414B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TIMOTHY NORRIS</creatorcontrib><creatorcontrib>JAMES J. 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Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMyM-pzM0vKsgoVshPUyjJSFUoKMpPKSpNVzDT9dPV8NF19HHUBZOauiVF-WWJaTn5FYnJmXk8DKxpiTnFqbxQmptBwc01xNlDN7UgPz61uCAxOTUvtSTeMdTM0szE0MTJyciYCCUAAycsWw</recordid><startdate>19980910</startdate><enddate>19980910</enddate><creator>TIMOTHY NORRIS</creator><creator>JAMES J. 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Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Polymorphs of the prodrug 6-N-(L-ALA-L-ALA)-trovafloxacin
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