4-amino-3-acyl quinoline derivatives

A compound of formula (I), wherein R denotes hydrogen, hydroxyl (OH), halogen or C1-4alkyl, R denotes hydrogen or C1-4alkyl, R denotes C1-4alkyl, A denotes methylene(-CH2-), ethylene (-CH2CH2-), ethylidene [-CH(CH3)-], trimethylene (-CH2CH2CH2-), oxyethylene (-O-CH2CH2-) or oxytrimethylene (-O-CH2CH...

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Hauptverfasser: JORG SENN-BILFINGER, GERHARD GRUNDLER, RICHARD RIEDEL, HARTMANN SCHAEFER, GEORG RAINER, ROBERT JOHN IFE, STEFEN POSTIUS, WOLFGANG ALEXANDER SIMON, COLIN ANDREW LEACH
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creator JORG SENN-BILFINGER
GERHARD GRUNDLER
RICHARD RIEDEL
HARTMANN SCHAEFER
GEORG RAINER
ROBERT JOHN IFE
STEFEN POSTIUS
WOLFGANG ALEXANDER SIMON
COLIN ANDREW LEACH
description A compound of formula (I), wherein R denotes hydrogen, hydroxyl (OH), halogen or C1-4alkyl, R denotes hydrogen or C1-4alkyl, R denotes C1-4alkyl, A denotes methylene(-CH2-), ethylene (-CH2CH2-), ethylidene [-CH(CH3)-], trimethylene (-CH2CH2CH2-), oxyethylene (-O-CH2CH2-) or oxytrimethylene (-O-CH2CH2CH2-), X denotes C1-6alkylene or C2-4alkenylene and Y denotes hydroxyl (OH) or amino (NH2), or a salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as inhibitors of gastric acid secretion.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 4-amino-3-acyl quinoline derivatives
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