Intermediates of ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
Isoxazole derivs. of formula (I) and their acid-addn. salts and solvates are new: In (I) R = 1-4C alkyl, allyl or cyclopropylmethyl; R1 = H, 1-4C alkyl, allyl, cyclopropylmethyl or aryl(1-4C)alkyl; X = CH2 or O; y = 4-R2-5-R3-3-isoxazolyl or 3-R2-4-R3-5-isoxazolyl; R2 and R3 = H, 1-4C alkyl, 1-4C al...
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| creator | ROBERT DANIEL TITUS DIANE LYNN HUSER JOHN MEHNERT SCHAUS CRAIG STEVEN HOECHSTETTER |
| description | Isoxazole derivs. of formula (I) and their acid-addn. salts and solvates are new: In (I) R = 1-4C alkyl, allyl or cyclopropylmethyl; R1 = H, 1-4C alkyl, allyl, cyclopropylmethyl or aryl(1-4C)alkyl; X = CH2 or O; y = 4-R2-5-R3-3-isoxazolyl or 3-R2-4-R3-5-isoxazolyl; R2 and R3 = H, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, OH, NH2, CN or Ph. Pref. x = CH2; R and R1 = 1-4C alkyl, esp. n-Pr; R2 and R3 = H. |
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Pref. x = CH2; R and R1 = 1-4C alkyl, esp. n-Pr; R2 and R3 = H.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Intermediates of ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes |
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