Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants

Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants

A composition comprising nanoparticles containing an x-ray diagnostic compound, having a high molecular weight surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith and methods of making nanoparticles is described. A preferred surfactant is...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GEORGE C. NA, NATARAJAN RAJAGOPALAN
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator GEORGE C. NA
NATARAJAN RAJAGOPALAN
description A composition comprising nanoparticles containing an x-ray diagnostic compound, having a high molecular weight surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith and methods of making nanoparticles is described. A preferred surfactant is poloxamine and preferred cloud point modifiers include dimyristoylphosphatidylglycerol and dioctylsulfosuccinate. A method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an x-ray an effective contrast producing amount of the above composition is also described.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU664115BB2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU664115BB2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU664115BB23</originalsourceid><addsrcrecordid>eNqNjDsOwkAMRNNQIOAOvkCK8OsJAlFRgUQXmcVJVtrYq7XD5_YkEgegGr3RvJlm77M8KUAtqesDmhfWEYCRJWIy78aa4JYn_MA9iDwgigRwwpZQDbAhNoVePTfQ-qaFTgKNWoIXDWzAwsOxd6B9qtEZDsI8m9QYlBa_nGVwPFz2p5yiVKQRHTFZtbtut-ui2JTlcvXH5AvdE0c_</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants</title><source>esp@cenet</source><creator>GEORGE C. NA ; NATARAJAN RAJAGOPALAN</creator><creatorcontrib>GEORGE C. NA ; NATARAJAN RAJAGOPALAN</creatorcontrib><description>A composition comprising nanoparticles containing an x-ray diagnostic compound, having a high molecular weight surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith and methods of making nanoparticles is described. A preferred surfactant is poloxamine and preferred cloud point modifiers include dimyristoylphosphatidylglycerol and dioctylsulfosuccinate. A method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an x-ray an effective contrast producing amount of the above composition is also described.</description><edition>5</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951102&amp;DB=EPODOC&amp;CC=AU&amp;NR=664115B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951102&amp;DB=EPODOC&amp;CC=AU&amp;NR=664115B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GEORGE C. NA</creatorcontrib><creatorcontrib>NATARAJAN RAJAGOPALAN</creatorcontrib><title>Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants</title><description>A composition comprising nanoparticles containing an x-ray diagnostic compound, having a high molecular weight surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith and methods of making nanoparticles is described. A preferred surfactant is poloxamine and preferred cloud point modifiers include dimyristoylphosphatidylglycerol and dioctylsulfosuccinate. A method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an x-ray an effective contrast producing amount of the above composition is also described.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDsOwkAMRNNQIOAOvkCK8OsJAlFRgUQXmcVJVtrYq7XD5_YkEgegGr3RvJlm77M8KUAtqesDmhfWEYCRJWIy78aa4JYn_MA9iDwgigRwwpZQDbAhNoVePTfQ-qaFTgKNWoIXDWzAwsOxd6B9qtEZDsI8m9QYlBa_nGVwPFz2p5yiVKQRHTFZtbtut-ui2JTlcvXH5AvdE0c_</recordid><startdate>19951102</startdate><enddate>19951102</enddate><creator>GEORGE C. NA</creator><creator>NATARAJAN RAJAGOPALAN</creator><scope>EVB</scope></search><sort><creationdate>19951102</creationdate><title>Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants</title><author>GEORGE C. NA ; NATARAJAN RAJAGOPALAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU664115BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1995</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>GEORGE C. NA</creatorcontrib><creatorcontrib>NATARAJAN RAJAGOPALAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GEORGE C. NA</au><au>NATARAJAN RAJAGOPALAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants</title><date>1995-11-02</date><risdate>1995</risdate><abstract>A composition comprising nanoparticles containing an x-ray diagnostic compound, having a high molecular weight surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith and methods of making nanoparticles is described. A preferred surfactant is poloxamine and preferred cloud point modifiers include dimyristoylphosphatidylglycerol and dioctylsulfosuccinate. A method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an x-ray an effective contrast producing amount of the above composition is also described.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_AU664115BB2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T10%3A51%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GEORGE%20C.%20NA&rft.date=1995-11-02&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU664115BB2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true