Boronic acid and ester inhibitors of thrombin

Novel boronic acid derivatives of formula (I), which are useful inhibitors of trypsin-like enzymes, are disclosed: R -Z-CHR -BY Y .

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Hauptverfasser: GREGORY JAMES PACOFSKY, EUGENE CRUZ AMPARO, WILLIAM HENRY MILLER, JOHN WITYAK
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creator GREGORY JAMES PACOFSKY
EUGENE CRUZ AMPARO
WILLIAM HENRY MILLER
JOHN WITYAK
description Novel boronic acid derivatives of formula (I), which are useful inhibitors of trypsin-like enzymes, are disclosed: R -Z-CHR -BY Y .
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title Boronic acid and ester inhibitors of thrombin
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