PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION
Compound are described of the general formula wherein R is a hydrogen atom or a C1-4 alkyl group; R is a naphthyl, thienyl or beta -styryl group or a group Ar(CH2)p- where p is zero or an integer from 1 to 3 and Ar is phenyl or phenyl substituted by one or more halogen atoms or C1-4 alkyl, C1-4 alko...
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creator | PETER HALLETT |
description | Compound are described of the general formula wherein R is a hydrogen atom or a C1-4 alkyl group; R is a naphthyl, thienyl or beta -styryl group or a group Ar(CH2)p- where p is zero or an integer from 1 to 3 and Ar is phenyl or phenyl substituted by one or more halogen atoms or C1-4 alkyl, C1-4 alkoxy, hydroxyl, trifluoromethyl, nitro or amino groups; m is an integer 1 or 2; n is an integer from 1 to 4; and the physiologically acceptable salts thereof. These compounds inhibit blood platelet aggregation, bronchoconstriction and vasoconstriction and thus of interest in the treatment of occlusive vascular diseases and asthma. |
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These compounds inhibit blood platelet aggregation, bronchoconstriction and vasoconstriction and thus of interest in the treatment of occlusive vascular diseases and asthma.</description><edition>4</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1990</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900201&DB=EPODOC&CC=AU&NR=593039B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900201&DB=EPODOC&CC=AU&NR=593039B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PETER HALLETT</creatorcontrib><title>PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION</title><description>Compound are described of the general formula wherein R is a hydrogen atom or a C1-4 alkyl group; R is a naphthyl, thienyl or beta -styryl group or a group Ar(CH2)p- where p is zero or an integer from 1 to 3 and Ar is phenyl or phenyl substituted by one or more halogen atoms or C1-4 alkyl, C1-4 alkoxy, hydroxyl, trifluoromethyl, nitro or amino groups; m is an integer 1 or 2; n is an integer from 1 to 4; and the physiologically acceptable salts thereof. These compounds inhibit blood platelet aggregation, bronchoconstriction and vasoconstriction and thus of interest in the treatment of occlusive vascular diseases and asthma.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1990</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgJ8HD184-IdPTxjvRxdgxyArJ9PJ0VHJ09XYIVHP1cFFyDQ1yDIMwQD1fPIIWAINcAxyDHEE9_P7BogIdjkK-js2toiKezo4-Cm3-Qb6gPWJqHgTUtMac4lRdKczMouLmGOHvophbkx6cWFyQmp-allsQ7hppaGhsYWzo5GRkToQQAmEIyjg</recordid><startdate>19900201</startdate><enddate>19900201</enddate><creator>PETER HALLETT</creator><scope>EVB</scope></search><sort><creationdate>19900201</creationdate><title>PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION</title><author>PETER HALLETT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU593039BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1990</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PETER HALLETT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PETER HALLETT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION</title><date>1990-02-01</date><risdate>1990</risdate><abstract>Compound are described of the general formula wherein R is a hydrogen atom or a C1-4 alkyl group; R is a naphthyl, thienyl or beta -styryl group or a group Ar(CH2)p- where p is zero or an integer from 1 to 3 and Ar is phenyl or phenyl substituted by one or more halogen atoms or C1-4 alkyl, C1-4 alkoxy, hydroxyl, trifluoromethyl, nitro or amino groups; m is an integer 1 or 2; n is an integer from 1 to 4; and the physiologically acceptable salts thereof. These compounds inhibit blood platelet aggregation, bronchoconstriction and vasoconstriction and thus of interest in the treatment of occlusive vascular diseases and asthma.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION |
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