Benzene, pyridine, naphtalene or benzophenone derivatives as inhibitors of squalene synthetase and protein farnesyltrans ferase

The present invention provides a compound of the formula which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates usef...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	DAVID M. STOUT, RAJNANDAN N. PRASAD, B. GREGORY DONNER, WANG SHEN, K. L. ANTHONY FUNG, STEPHEN A. FAKHOURY, WILLIAM R. BAKER, TODD W. ROCKWAY, DAVID S GARVEY, STEPHEN J. O'CONNOR, GERARD M. SULLIVAN, SAUL H. ROSENBERG
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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