Estra-1,3,5(10)-triene derivatives

Estra-1,3,5(10)-triene derivatives

Provided is steroid sulfatase inhibitors comprising, as the active ingredient, an estra-1,3,5(10)-triene derivative which is represented by formula (I): äwherein R and R are the same or different and represent a hydrogen atom, a lower alkyl group or, etc.; R represents a hydrogen atom etc.; R repres...

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Bibliographische Detailangaben
Hauptverfasser: CHIKARA MURAKATA, KOZUE HAYASHI, SHIRO AKINAGA, MAYUMI MIYATA, TSUTOMU AGATSUMA, NOBUYOSHI AMISHIRO, YOJI INO, TAKESHI TAKAHASHI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Beschreibung
Zusammenfassung:Provided is steroid sulfatase inhibitors comprising, as the active ingredient, an estra-1,3,5(10)-triene derivative which is represented by formula (I): äwherein R and R are the same or different and represent a hydrogen atom, a lower alkyl group or, etc.; R represents a hydrogen atom etc.; R represents a hydrogen atom etc.; R represents a hydrogen atom etc.; R represents a cyano group, an amino group, COR (wherein R represents a substituted lower alkyl group etc.), a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic group, etcü, or pharmaceutically acceptable salts thereof.