Therapeutically useful new salts of cck inhibitors, process for the preparation thereof and pharmaceutical preparations containing them

Therapeutically useful new salts of cck inhibitors, process for the preparation thereof and pharmaceutical preparations containing them

Salts of 2-(((4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexyl-ethyl)-2-thiazolyl)amino)carbonyl)-5,7-dimethyl-1H-indol-1-acetic acid (I), their solvates, polymorphs and pseudo polymorphs are new. Salts of 2-(((4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexyl-ethyl)-2-thiazolyl)amino)carbonyl)-5,7...

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Hauptverfasser: MIKLOS MORVAI, ISTVAN HERMECZ, BENJAMIN PODANYI, AGOTA SMELKONE ESEK, GYULANE KISS, KALMAN SIMON, AGNES HORVATH, ARPADNE VASVARI, ANNA SZABO, JUDIT SIPOS
Format: Patent
Sprache:eng
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Zusammenfassung:Salts of 2-(((4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexyl-ethyl)-2-thiazolyl)amino)carbonyl)-5,7-dimethyl-1H-indol-1-acetic acid (I), their solvates, polymorphs and pseudo polymorphs are new. Salts of 2-(((4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexyl-ethyl)-2-thiazolyl)amino)carbonyl)-5,7-dimethyl-1H-indol-1-acetic acid of formula (I), their solvates, polymorphs and pseudo polymorphs are new. [Image] X : ethanolamine, diethanolamine or diethylamine. ACTIVITY : Gastrointestinal; Cerebroprotective. MECHANISM OF ACTION : Cholecystokinin A agonist. No biological data given.