Oligoribonucleotide and ribozyme analogs with terminal 3'-3' and/or 5'-5' linkages

The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where ap...

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Hauptverfasser: FLAVIO RAMALHO ORTIGAO, HANNELORE ROSCH, BERND KRIST, RUDI ROSCH, H. SELIGER
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creator FLAVIO RAMALHO ORTIGAO
HANNELORE ROSCH
BERND KRIST
RUDI ROSCH
H. SELIGER
description The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where appropriate.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title Oligoribonucleotide and ribozyme analogs with terminal 3'-3' and/or 5'-5' linkages
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