Lk6-a derivatives
LK6-A derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, which exhibit immunosuppressive, cytostatic and antitumor effects and so on, wherein R is a lower alkanoyl or acryloyl group which may be substituted with, e.g., lower alkoxy, or the like; R is hydro...
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| creator | KENICHI MOCHIDA YUTAKA KANDA TSUTOMU AKAMA SHUN-ICHI IKEDA ISAMI TAKAHASHI HIROYUKI NAGATA HARUMI UE ATSUHIRO HASEGAWA YUTAKA SAITOH |
| description | LK6-A derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, which exhibit immunosuppressive, cytostatic and antitumor effects and so on, wherein R is a lower alkanoyl or acryloyl group which may be substituted with, e.g., lower alkoxy, or the like; R is hydrogen, halogeno or the like; R together with R forms a bond; R is optionally substituted lower alkanoyl, or R together with R and R together form a bond is excepted. |
| format | Patent |
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R is hydrogen, halogeno or the like; R<2'> is hydrogen, or R<2'> together with R forms a bond; R is optionally substituted lower alkanoyl, or R together with R<2'> forms a bond; R and R are each hydrogen, optionally substituted lower alkanoyl or the like; R is hydrogen or the like; and R and R are each hydrogen, optionally substituted lower alkanoyl or the like, with the proviso that LK6-A corresponding to a compound of general formula (I) where R is (E)-methoxyacryloyl; R , R , R , R and R are each hydrogen; R is acetyl; and R<2'> and R together form a bond is excepted.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2000</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000201&DB=EPODOC&CC=AU&NR=4650099A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000201&DB=EPODOC&CC=AU&NR=4650099A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KENICHI MOCHIDA</creatorcontrib><creatorcontrib>YUTAKA KANDA</creatorcontrib><creatorcontrib>TSUTOMU AKAMA</creatorcontrib><creatorcontrib>SHUN-ICHI IKEDA</creatorcontrib><creatorcontrib>ISAMI TAKAHASHI</creatorcontrib><creatorcontrib>HIROYUKI NAGATA</creatorcontrib><creatorcontrib>HARUMI UE</creatorcontrib><creatorcontrib>ATSUHIRO HASEGAWA</creatorcontrib><creatorcontrib>YUTAKA SAITOH</creatorcontrib><title>Lk6-a derivatives</title><description>LK6-A derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, which exhibit immunosuppressive, cytostatic and antitumor effects and so on, wherein R is a lower alkanoyl or acryloyl group which may be substituted with, e.g., lower alkoxy, or the like; R is hydrogen, halogeno or the like; R<2'> is hydrogen, or R<2'> together with R forms a bond; R is optionally substituted lower alkanoyl, or R together with R<2'> forms a bond; R and R are each hydrogen, optionally substituted lower alkanoyl or the like; R is hydrogen or the like; and R and R are each hydrogen, optionally substituted lower alkanoyl or the like, with the proviso that LK6-A corresponding to a compound of general formula (I) where R is (E)-methoxyacryloyl; R , R , R , R and R are each hydrogen; R is acetyl; and R<2'> and R together form a bond is excepted.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2000</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD0yTbTTVRISS3KLEssySxLLeZhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfGOoSZmpgYGlpaOxoRVAAA0hh6B</recordid><startdate>20000201</startdate><enddate>20000201</enddate><creator>KENICHI MOCHIDA</creator><creator>YUTAKA KANDA</creator><creator>TSUTOMU AKAMA</creator><creator>SHUN-ICHI IKEDA</creator><creator>ISAMI TAKAHASHI</creator><creator>HIROYUKI NAGATA</creator><creator>HARUMI UE</creator><creator>ATSUHIRO HASEGAWA</creator><creator>YUTAKA SAITOH</creator><scope>EVB</scope></search><sort><creationdate>20000201</creationdate><title>Lk6-a derivatives</title><author>KENICHI MOCHIDA ; 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R is hydrogen, halogeno or the like; R<2'> is hydrogen, or R<2'> together with R forms a bond; R is optionally substituted lower alkanoyl, or R together with R<2'> forms a bond; R and R are each hydrogen, optionally substituted lower alkanoyl or the like; R is hydrogen or the like; and R and R are each hydrogen, optionally substituted lower alkanoyl or the like, with the proviso that LK6-A corresponding to a compound of general formula (I) where R is (E)-methoxyacryloyl; R , R , R , R and R are each hydrogen; R is acetyl; and R<2'> and R together form a bond is excepted.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Lk6-a derivatives |
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