Inhibition of the degradation of connective tissue matrix protein components in mammals

Inhibition of the degradation of connective tissue matrix protein components in mammals

Bis-phosphonates such as clodronate, etidronate, pamidronate and alendronate are found to inhibit the degradation of connective tissue matrix protein components in mammals, including humans, and therefore are useful in the therapeutic and prophylactic treatment of mammals against a variety of physio...

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Hauptverfasser: TUULA ANNELI SALO, OLLI PEKKA TERONEN, TIMO ARTO SORSA
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Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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creator TUULA ANNELI SALO
OLLI PEKKA TERONEN
TIMO ARTO SORSA
description Bis-phosphonates such as clodronate, etidronate, pamidronate and alendronate are found to inhibit the degradation of connective tissue matrix protein components in mammals, including humans, and therefore are useful in the therapeutic and prophylactic treatment of mammals against a variety of physiological and pathological connective tissue disorders or extracellular protein degradation disorders including wounds, burns, fractures, lesions, ulcers, cancer and metastasis progression in connective tissues, rheumatoid arthritis and other arthitides, periodontitis, peri-implantitis, cysts, root canal treatment, AIDS, ulceration of the cornea, gastric ulceration, aftae, trauma, acne, psoriasis, loosening of end-osseal hip-protheses.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title Inhibition of the degradation of connective tissue matrix protein components in mammals
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