Expression of dna or proteins in (c. elegans)

DNA fragments from the promoter region of the C. elegans UL6 gene which are capable of functioning as promoters directing gene expression in the excretory cell of C. elegans are provided and also expression vectors and transgenic C. elegans containing these fragments. Also provided are screening met...

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Bibliographische Detailangaben
Hauptverfasser:	INGELE ROELENS, RICHARD ZWAAL, THIERRY BOGAERT, WOUTER ASAERT
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	DNA fragments from the promoter region of the C. elegans UL6 gene which are capable of functioning as promoters directing gene expression in the excretory cell of C. elegans are provided and also expression vectors and transgenic C. elegans containing these fragments. Also provided are screening methods performed in C. elegans for identifying compounds or mutations which have an affect on the morphology of the excretory canal. Compounds identified using these screening methods may have therapeutic potential in the treatment of a range of diseases for which the C. elegans excretory canal serves as a model.