TOCOLYTIC MEANS

The invention relates to tetrahydroisoquinoline derivatives of the Formula wherein R1, R2, R3 and R4 are each selected from the group consisting of a hydrogen and a hydroxyl group. These derivatives are useful in tocology (obstetrics). Administration of the inventive compounds induces relaxation of...

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Hauptverfasser:	ORHIDEYA BONTECHEVA ZABUNOVA, NEDYALKA STOYANOVA IVANOVA, MILKA PETROVA NIKOLOVA, MARGARITA DIMITROVA DRYANSKA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	ORHIDEYA BONTECHEVA ZABUNOVA NEDYALKA STOYANOVA IVANOVA MILKA PETROVA NIKOLOVA MARGARITA DIMITROVA DRYANSKA
description	The invention relates to tetrahydroisoquinoline derivatives of the Formula wherein R1, R2, R3 and R4 are each selected from the group consisting of a hydrogen and a hydroxyl group. These derivatives are useful in tocology (obstetrics). Administration of the inventive compounds induces relaxation of uterine muscles, a property that is particularly useful in cases of second trimester miscarriage, premature birth up to the 37th or 38th week of pregnancy, and during delivery. The compounds are especially useful from the onset of labor up to delivery of the newborn's head, a period which is often accompanied or complicated by frequent, violent, uncoordinated contractions of the uterus. The compounds are also useful in obstetric and gynecological operations, such as a hysterectomy, surgery for acute placental insufficiency, etc.
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These derivatives are useful in tocology (obstetrics). Administration of the inventive compounds induces relaxation of uterine muscles, a property that is particularly useful in cases of second trimester miscarriage, premature birth up to the 37th or 38th week of pregnancy, and during delivery. The compounds are especially useful from the onset of labor up to delivery of the newborn's head, a period which is often accompanied or complicated by frequent, violent, uncoordinated contractions of the uterus. 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The compounds are also useful in obstetric and gynecological operations, such as a hysterectomy, surgery for acute placental insufficiency, etc.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1985</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOAP8Xf294kM8XRW8HV19AvmYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxjqFGlqbmJhYmjsaEVQAAgMIcmA</recordid><startdate>19850103</startdate><enddate>19850103</enddate><creator>ORHIDEYA BONTECHEVA ZABUNOVA</creator><creator>NEDYALKA STOYANOVA IVANOVA</creator><creator>MILKA PETROVA NIKOLOVA</creator><creator>MARGARITA DIMITROVA DRYANSKA</creator><scope>EVB</scope></search><sort><creationdate>19850103</creationdate><title>TOCOLYTIC MEANS</title><author>ORHIDEYA BONTECHEVA ZABUNOVA ; NEDYALKA STOYANOVA IVANOVA ; MILKA PETROVA NIKOLOVA ; MARGARITA DIMITROVA DRYANSKA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2957484A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1985</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ORHIDEYA BONTECHEVA ZABUNOVA</creatorcontrib><creatorcontrib>NEDYALKA STOYANOVA IVANOVA</creatorcontrib><creatorcontrib>MILKA PETROVA NIKOLOVA</creatorcontrib><creatorcontrib>MARGARITA DIMITROVA DRYANSKA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ORHIDEYA BONTECHEVA ZABUNOVA</au><au>NEDYALKA STOYANOVA IVANOVA</au><au>MILKA PETROVA NIKOLOVA</au><au>MARGARITA DIMITROVA DRYANSKA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TOCOLYTIC MEANS</title><date>1985-01-03</date><risdate>1985</risdate><abstract>The invention relates to tetrahydroisoquinoline derivatives of the Formula wherein R1, R2, R3 and R4 are each selected from the group consisting of a hydrogen and a hydroxyl group. 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	TOCOLYTIC MEANS
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