Inhibition of the binding of human ige to its receptor by tetracyclic compounds for the alleviation of ige-mediated immune response
Disclosed are chemical agents with unexpected activity to inhibit the interactions between human immunoglobulin E (IgE) and its receptor (Fc epsilon RI) which interactions are known to be involved in triggering allergic responses. The agents may be used to module the allergic response in the treatme...
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