Bioactive and/or targeted dendrimer conjugates
Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present t...
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| creator | HERBERT M. BROTHERS II LARRY R. WILSON DONALD A. TOMALIA DONALD A. KAPLAN ROBERTA C. CHENG MICHAEL J. FAZIO SCOTT L KLAKAMP LARS T PIEHLER RUI YIN ANNA U BIELINSKA IAN A. TOMLINSON BARTLEY D MAXON JAMES R. BAKER JOLANTA KUKOWSKA-LATALLO JENNIFER A JOHNSON DAVID M. HEDSTRAND WILLIAM J. JR KRUPER |
| description | Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2118195A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2118195A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2118195A3</originalsourceid><addsrcrecordid>eNrjZNBzysxPTC7JLEtVSMxL0c8vUihJLEpPLUlNUUhJzUspysxNLVJIzs_LKk1PLEkt5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8Y6hRoaGFoaWpo7GhFUAAF8UKec</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Bioactive and/or targeted dendrimer conjugates</title><source>esp@cenet</source><creator>HERBERT M. BROTHERS II ; LARRY R. WILSON ; DONALD A. TOMALIA ; DONALD A. KAPLAN ; ROBERTA C. CHENG ; MICHAEL J. FAZIO ; SCOTT L KLAKAMP ; LARS T PIEHLER ; RUI YIN ; ANNA U BIELINSKA ; IAN A. TOMLINSON ; BARTLEY D MAXON ; JAMES R. BAKER ; JOLANTA KUKOWSKA-LATALLO ; JENNIFER A JOHNSON ; DAVID M. HEDSTRAND ; WILLIAM J. JR KRUPER</creator><creatorcontrib>HERBERT M. BROTHERS II ; LARRY R. WILSON ; DONALD A. TOMALIA ; DONALD A. KAPLAN ; ROBERTA C. CHENG ; MICHAEL J. FAZIO ; SCOTT L KLAKAMP ; LARS T PIEHLER ; RUI YIN ; ANNA U BIELINSKA ; IAN A. TOMLINSON ; BARTLEY D MAXON ; JAMES R. BAKER ; JOLANTA KUKOWSKA-LATALLO ; JENNIFER A JOHNSON ; DAVID M. HEDSTRAND ; WILLIAM J. JR KRUPER</creatorcontrib><description>Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.</description><edition>6</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PEPTIDES ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; THEIR PREPARATION OR CHEMICAL WORKING-UP ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950925&DB=EPODOC&CC=AU&NR=2118195A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950925&DB=EPODOC&CC=AU&NR=2118195A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HERBERT M. BROTHERS II</creatorcontrib><creatorcontrib>LARRY R. WILSON</creatorcontrib><creatorcontrib>DONALD A. TOMALIA</creatorcontrib><creatorcontrib>DONALD A. KAPLAN</creatorcontrib><creatorcontrib>ROBERTA C. CHENG</creatorcontrib><creatorcontrib>MICHAEL J. FAZIO</creatorcontrib><creatorcontrib>SCOTT L KLAKAMP</creatorcontrib><creatorcontrib>LARS T PIEHLER</creatorcontrib><creatorcontrib>RUI YIN</creatorcontrib><creatorcontrib>ANNA U BIELINSKA</creatorcontrib><creatorcontrib>IAN A. TOMLINSON</creatorcontrib><creatorcontrib>BARTLEY D MAXON</creatorcontrib><creatorcontrib>JAMES R. BAKER</creatorcontrib><creatorcontrib>JOLANTA KUKOWSKA-LATALLO</creatorcontrib><creatorcontrib>JENNIFER A JOHNSON</creatorcontrib><creatorcontrib>DAVID M. HEDSTRAND</creatorcontrib><creatorcontrib>WILLIAM J. JR KRUPER</creatorcontrib><title>Bioactive and/or targeted dendrimer conjugates</title><description>Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>COMPOSITIONS OF MACROMOLECULAR COMPOUNDS</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PEPTIDES</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><subject>TRAPPING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBzysxPTC7JLEtVSMxL0c8vUihJLEpPLUlNUUhJzUspysxNLVJIzs_LKk1PLEkt5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8Y6hRoaGFoaWpo7GhFUAAF8UKec</recordid><startdate>19950925</startdate><enddate>19950925</enddate><creator>HERBERT M. BROTHERS II</creator><creator>LARRY R. WILSON</creator><creator>DONALD A. TOMALIA</creator><creator>DONALD A. KAPLAN</creator><creator>ROBERTA C. CHENG</creator><creator>MICHAEL J. FAZIO</creator><creator>SCOTT L KLAKAMP</creator><creator>LARS T PIEHLER</creator><creator>RUI YIN</creator><creator>ANNA U BIELINSKA</creator><creator>IAN A. TOMLINSON</creator><creator>BARTLEY D MAXON</creator><creator>JAMES R. BAKER</creator><creator>JOLANTA KUKOWSKA-LATALLO</creator><creator>JENNIFER A JOHNSON</creator><creator>DAVID M. HEDSTRAND</creator><creator>WILLIAM J. JR KRUPER</creator><scope>EVB</scope></search><sort><creationdate>19950925</creationdate><title>Bioactive and/or targeted dendrimer conjugates</title><author>HERBERT M. BROTHERS II ; LARRY R. WILSON ; DONALD A. TOMALIA ; DONALD A. KAPLAN ; ROBERTA C. CHENG ; MICHAEL J. FAZIO ; SCOTT L KLAKAMP ; LARS T PIEHLER ; RUI YIN ; ANNA U BIELINSKA ; IAN A. TOMLINSON ; BARTLEY D MAXON ; JAMES R. BAKER ; JOLANTA KUKOWSKA-LATALLO ; JENNIFER A JOHNSON ; DAVID M. HEDSTRAND ; WILLIAM J. JR KRUPER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2118195A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1995</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>COMPOSITIONS OF MACROMOLECULAR COMPOUNDS</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PEPTIDES</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>TRAPPING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>HERBERT M. BROTHERS II</creatorcontrib><creatorcontrib>LARRY R. WILSON</creatorcontrib><creatorcontrib>DONALD A. TOMALIA</creatorcontrib><creatorcontrib>DONALD A. KAPLAN</creatorcontrib><creatorcontrib>ROBERTA C. CHENG</creatorcontrib><creatorcontrib>MICHAEL J. FAZIO</creatorcontrib><creatorcontrib>SCOTT L KLAKAMP</creatorcontrib><creatorcontrib>LARS T PIEHLER</creatorcontrib><creatorcontrib>RUI YIN</creatorcontrib><creatorcontrib>ANNA U BIELINSKA</creatorcontrib><creatorcontrib>IAN A. TOMLINSON</creatorcontrib><creatorcontrib>BARTLEY D MAXON</creatorcontrib><creatorcontrib>JAMES R. BAKER</creatorcontrib><creatorcontrib>JOLANTA KUKOWSKA-LATALLO</creatorcontrib><creatorcontrib>JENNIFER A JOHNSON</creatorcontrib><creatorcontrib>DAVID M. HEDSTRAND</creatorcontrib><creatorcontrib>WILLIAM J. JR KRUPER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HERBERT M. BROTHERS II</au><au>LARRY R. WILSON</au><au>DONALD A. TOMALIA</au><au>DONALD A. KAPLAN</au><au>ROBERTA C. CHENG</au><au>MICHAEL J. FAZIO</au><au>SCOTT L KLAKAMP</au><au>LARS T PIEHLER</au><au>RUI YIN</au><au>ANNA U BIELINSKA</au><au>IAN A. TOMLINSON</au><au>BARTLEY D MAXON</au><au>JAMES R. BAKER</au><au>JOLANTA KUKOWSKA-LATALLO</au><au>JENNIFER A JOHNSON</au><au>DAVID M. HEDSTRAND</au><au>WILLIAM J. JR KRUPER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Bioactive and/or targeted dendrimer conjugates</title><date>1995-09-25</date><risdate>1995</risdate><abstract>Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP TRAPPING VINEGAR WINE |
| title | Bioactive and/or targeted dendrimer conjugates |
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