EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF

Abstract The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (1): wherein X", Z1, Z2, n, R1, R2, R3, R4, R 5, R6, R7, and R8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and ade...

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Bibliographische Detailangaben
Hauptverfasser: Cunningham, Richard, Erickson, Aron, Redpath, Philip, Nygaard, Richard, Migaud, Marie Eugenie, Crossey, Kerri, Storjohann, Amanda
Format: Patent
Sprache:eng
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