Controlled porosity devices for tissue treatments, methods of use, and methods of manufacture

A balloon comprising: a first porous membrane comprising a first microstructure, the first microstructure being configured to inflate to a nominal dimension in response to introduction of a fluid at an inflation pressure and an inflation rate, and resist fluid flow at pressures below a threshold per...

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Bibliographische Detailangaben
Hauptverfasser: CULLY, Edward H, BACINO, John E, VONESH, Michael J, CAMPBELL, Carey V, TRAPP, Benjamin M
Format: Patent
Sprache:eng
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Zusammenfassung:A balloon comprising: a first porous membrane comprising a first microstructure, the first microstructure being configured to inflate to a nominal dimension in response to introduction of a fluid at an inflation pressure and an inflation rate, and resist fluid flow at pressures below a threshold perfusion pressure at which perfusion begins; and a second porous membrane compirisng a second microstructure that is different from the first microstructure, the second microstructure being configured to withstand a hydrostatic load generated by the first porous membrane upon inflation, wherein the threshold perfusion pressure is equal to or greater than the inflation pressure required to achieve the nominal dimension, and a terminal pressure at which a maximum working pressure of the balloon is exceeded is greater than the threshold perfusion pressure. 20695504_1 (GHMatters) P96537.AU.6 FIG.l1A