SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME

The disclosure provides at least one compound, tautomer, deuterated derivative, or pharmaceutically acceptable salt chosen from compounds of Formula I, tautomers thereof, deuterated derivatives of those compounds or tautomers, and pharmaceutically acceptable salts of any of the foregoing, compositio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	WANG, Tiansheng, SENTER, Timothy J, NAMIREMBE, Sheila, WANG, Haoxuan, CHEN, Ming, GALE-DAY, Zachary, OLSEN, Jessica H, DAKIN, Leslie A, SHIMIZU, Akira J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	WANG, Tiansheng SENTER, Timothy J NAMIREMBE, Sheila WANG, Haoxuan CHEN, Ming GALE-DAY, Zachary OLSEN, Jessica H DAKIN, Leslie A SHIMIZU, Akira J
description	The disclosure provides at least one compound, tautomer, deuterated derivative, or pharmaceutically acceptable salt chosen from compounds of Formula I, tautomers thereof, deuterated derivatives of those compounds or tautomers, and pharmaceutically acceptable salts of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2023218940A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2023218940A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2023218940A13</originalsourceid><addsrcrecordid>eNrjZPANDvAM8lcI8AxwDfJ08fRzVXABMsIcQzzDXIMVHIMVPP08PJ08Q_yDghX83RQcA_x9DBUc_VwUfF1DPPxdwIKhwZ5-7grBjr6uPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7Uk3jHUyMDI2MjQwtLEwNHQmDhVAItALsc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME</title><source>esp@cenet</source><creator>WANG, Tiansheng ; SENTER, Timothy J ; NAMIREMBE, Sheila ; WANG, Haoxuan ; CHEN, Ming ; GALE-DAY, Zachary ; OLSEN, Jessica H ; DAKIN, Leslie A ; SHIMIZU, Akira J</creator><creatorcontrib>WANG, Tiansheng ; SENTER, Timothy J ; NAMIREMBE, Sheila ; WANG, Haoxuan ; CHEN, Ming ; GALE-DAY, Zachary ; OLSEN, Jessica H ; DAKIN, Leslie A ; SHIMIZU, Akira J</creatorcontrib><description>The disclosure provides at least one compound, tautomer, deuterated derivative, or pharmaceutically acceptable salt chosen from compounds of Formula I, tautomers thereof, deuterated derivatives of those compounds or tautomers, and pharmaceutically acceptable salts of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240822&DB=EPODOC&CC=AU&NR=2023218940A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240822&DB=EPODOC&CC=AU&NR=2023218940A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, Tiansheng</creatorcontrib><creatorcontrib>SENTER, Timothy J</creatorcontrib><creatorcontrib>NAMIREMBE, Sheila</creatorcontrib><creatorcontrib>WANG, Haoxuan</creatorcontrib><creatorcontrib>CHEN, Ming</creatorcontrib><creatorcontrib>GALE-DAY, Zachary</creatorcontrib><creatorcontrib>OLSEN, Jessica H</creatorcontrib><creatorcontrib>DAKIN, Leslie A</creatorcontrib><creatorcontrib>SHIMIZU, Akira J</creatorcontrib><title>SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME</title><description>The disclosure provides at least one compound, tautomer, deuterated derivative, or pharmaceutically acceptable salt chosen from compounds of Formula I, tautomers thereof, deuterated derivatives of those compounds or tautomers, and pharmaceutically acceptable salts of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPANDvAM8lcI8AxwDfJ08fRzVXABMsIcQzzDXIMVHIMVPP08PJ08Q_yDghX83RQcA_x9DBUc_VwUfF1DPPxdwIKhwZ5-7grBjr6uPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7Uk3jHUyMDI2MjQwtLEwNHQmDhVAItALsc</recordid><startdate>20240822</startdate><enddate>20240822</enddate><creator>WANG, Tiansheng</creator><creator>SENTER, Timothy J</creator><creator>NAMIREMBE, Sheila</creator><creator>WANG, Haoxuan</creator><creator>CHEN, Ming</creator><creator>GALE-DAY, Zachary</creator><creator>OLSEN, Jessica H</creator><creator>DAKIN, Leslie A</creator><creator>SHIMIZU, Akira J</creator><scope>EVB</scope></search><sort><creationdate>20240822</creationdate><title>SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME</title><author>WANG, Tiansheng ; SENTER, Timothy J ; NAMIREMBE, Sheila ; WANG, Haoxuan ; CHEN, Ming ; GALE-DAY, Zachary ; OLSEN, Jessica H ; DAKIN, Leslie A ; SHIMIZU, Akira J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2023218940A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, Tiansheng</creatorcontrib><creatorcontrib>SENTER, Timothy J</creatorcontrib><creatorcontrib>NAMIREMBE, Sheila</creatorcontrib><creatorcontrib>WANG, Haoxuan</creatorcontrib><creatorcontrib>CHEN, Ming</creatorcontrib><creatorcontrib>GALE-DAY, Zachary</creatorcontrib><creatorcontrib>OLSEN, Jessica H</creatorcontrib><creatorcontrib>DAKIN, Leslie A</creatorcontrib><creatorcontrib>SHIMIZU, Akira J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, Tiansheng</au><au>SENTER, Timothy J</au><au>NAMIREMBE, Sheila</au><au>WANG, Haoxuan</au><au>CHEN, Ming</au><au>GALE-DAY, Zachary</au><au>OLSEN, Jessica H</au><au>DAKIN, Leslie A</au><au>SHIMIZU, Akira J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME</title><date>2024-08-22</date><risdate>2024</risdate><abstract>The disclosure provides at least one compound, tautomer, deuterated derivative, or pharmaceutically acceptable salt chosen from compounds of Formula I, tautomers thereof, deuterated derivatives of those compounds or tautomers, and pharmaceutically acceptable salts of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng
recordid	cdi_epo_espacenet_AU2023218940A1
source	esp@cenet
subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-04T00%3A00%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=WANG,%20Tiansheng&rft.date=2024-08-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2023218940A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true