PLASMA KALLIKREIN INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary ang...
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| creator | CERNAKA, Natalija LOPEZ, Jovan TIAN, Maoqun MANDAL, Mihir GAO, Ying-Duo OGAWA, Anthony SHARP, Phillip BAO, Jianming TANG, Haiqun XIAO, Dong YANG, Song SINZ, Christopher HE, Jiafang CHENG, Alan MERCHANT, Rohan |
| description | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age-related macular degeneration, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein. |
| format | Patent |
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The compounds are selective inhibitors of plasma kallikrein.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240711&DB=EPODOC&CC=AU&NR=2023211555A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240711&DB=EPODOC&CC=AU&NR=2023211555A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CERNAKA, Natalija</creatorcontrib><creatorcontrib>LOPEZ, Jovan</creatorcontrib><creatorcontrib>TIAN, Maoqun</creatorcontrib><creatorcontrib>MANDAL, Mihir</creatorcontrib><creatorcontrib>GAO, Ying-Duo</creatorcontrib><creatorcontrib>OGAWA, Anthony</creatorcontrib><creatorcontrib>SHARP, Phillip</creatorcontrib><creatorcontrib>BAO, Jianming</creatorcontrib><creatorcontrib>TANG, Haiqun</creatorcontrib><creatorcontrib>XIAO, Dong</creatorcontrib><creatorcontrib>YANG, Song</creatorcontrib><creatorcontrib>SINZ, Christopher</creatorcontrib><creatorcontrib>HE, Jiafang</creatorcontrib><creatorcontrib>CHENG, Alan</creatorcontrib><creatorcontrib>MERCHANT, Rohan</creatorcontrib><title>PLASMA KALLIKREIN INHIBITORS</title><description>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age-related macular degeneration, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. 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The compounds are selective inhibitors of plasma kallikrein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PLASMA KALLIKREIN INHIBITORS |
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