Compositions and methods related to anti-CD19 antibody drug conjugates
Abstract The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-CD 19 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal ant...
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| creator | KIM, Sung Min CHAE, Jeiwook FISCHER, Nicolas KIM, Hyoung Rae OH, Yeong Soo PARK, Yun Hee DEEHAN, Maureen OH, Ji Hye SONG, Ho Young RYU, Hyun Min KIM, Yong Zu |
| description | Abstract The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-CD 19 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind CD 19, as well as methods of making and using tltese anti-CD 19 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications. |
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The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind CD 19, as well as methods of making and using tltese anti-CD 19 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230511&DB=EPODOC&CC=AU&NR=2023202448A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230511&DB=EPODOC&CC=AU&NR=2023202448A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, Sung Min</creatorcontrib><creatorcontrib>CHAE, Jeiwook</creatorcontrib><creatorcontrib>FISCHER, Nicolas</creatorcontrib><creatorcontrib>KIM, Hyoung Rae</creatorcontrib><creatorcontrib>OH, Yeong Soo</creatorcontrib><creatorcontrib>PARK, Yun Hee</creatorcontrib><creatorcontrib>DEEHAN, Maureen</creatorcontrib><creatorcontrib>OH, Ji Hye</creatorcontrib><creatorcontrib>SONG, Ho Young</creatorcontrib><creatorcontrib>RYU, Hyun Min</creatorcontrib><creatorcontrib>KIM, Yong Zu</creatorcontrib><title>Compositions and methods related to anti-CD19 antibody drug conjugates</title><description>Abstract The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-CD 19 antibody through a linker. 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The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind CD 19, as well as methods of making and using tltese anti-CD 19 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Compositions and methods related to anti-CD19 antibody drug conjugates |
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