COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF

The present disclosure provides: a compound of a specific chemical structure, having excellent activity with respect to BTK degradation; or a pharmaceutically acceptable salt thereof. The present disclosure also provides a composition comprising the compound or pharmaceutically acceptable salts ther...

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Hauptverfasser: LEE, Ho Hyun, KIM, So Hyuk, KIM, Han Wool, AHN, Jung Min, YOO, Sun Mi, RYU, Je Ho, YUN, Whee Sahng, CHOI, Ae Ran, LIM, Ye Seul, LEE, Song Hee, MOON, Hee Jung, KIM, Ye Eun, JANG, Mi Young, JEONG, Na Rae
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creator LEE, Ho Hyun
KIM, So Hyuk
KIM, Han Wool
AHN, Jung Min
YOO, Sun Mi
RYU, Je Ho
YUN, Whee Sahng
CHOI, Ae Ran
LIM, Ye Seul
LEE, Song Hee
MOON, Hee Jung
KIM, Ye Eun
JANG, Mi Young
JEONG, Na Rae
description The present disclosure provides: a compound of a specific chemical structure, having excellent activity with respect to BTK degradation; or a pharmaceutically acceptable salt thereof. The present disclosure also provides a composition comprising the compound or pharmaceutically acceptable salts thereof. The present disclosure also provides are pharmaceutical use for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer) of the compound, the salt thereof, and the composition comprising same according to the present disclosure. The present disclosure also provides a method for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer), comprising administering, to a subject requiring treatment, an effective amount of the compound, the salt thereof, or the composition comprising same according to the present disclosure.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF
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