ACTIVATABLE CYTOKINE CONSTRUCTS AND COMBINATION METHODS

Provided herein are methods of treating a subject by administering a combination of an activatable cytokine construct (ACC) and a PD-1/PD-L1 pathway inhibitor in which the ACC includes: a first monomer construct including an optional first peptide mask (PM1), an optional third cleavable moiety (CM3)...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	BEREZHNOY, Alexey Yevgenyevich, WONG, Kenneth, PAIDHUNGAT, Madan M, LAPUYADE, Nicole G, LE SCOLAN, Erwan, WINTER, Michael B, DANIEL, Dylan L, CAI, Na
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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