FUSED HETEROCYCLIC RINGS AS RIPK1 INHIBITORS

The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therape...

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Hauptverfasser: PARK, Kitae, KIM, Minha, SEO, Jeongbeob, HAN, Cheolkyu, CHOI, Sungmin, KIM, Jinyoung, JEON, Seeun, KWON, Youngeun, KANG, Hongjun, JEONG, Heejin, YOON, Cheolhwan, KIM, Sunjoo, KIM, Namhee, HAN, Sangbae, MIN, Jiae, YANG, Inho
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creator PARK, Kitae
KIM, Minha
SEO, Jeongbeob
HAN, Cheolkyu
CHOI, Sungmin
KIM, Jinyoung
JEON, Seeun
KWON, Youngeun
KANG, Hongjun
JEONG, Heejin
YOON, Cheolhwan
KIM, Sunjoo
KIM, Namhee
HAN, Sangbae
MIN, Jiae
YANG, Inho
description The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therapeutic methods.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FUSED HETEROCYCLIC RINGS AS RIPK1 INHIBITORS
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