MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER
The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer.
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| creator | KUZMANOV, Ivan SPIRES, Vanessa LABRIJN, Aran Frank BLUM, Jordan FELLERMEIER-KOPF, Sina SAHIN, Ugur PAULMANN, Claudia HIGGS, Brandon FERESHTEH, Mark NIEWOOD, Michelle BECKMANN, Karsten MUIK, Alexander HIBBERT, Richard GARRIDO CASTRO, Patricia BAJAJ, Gaurav DE KREUK, Bart-Jan ADAMS, Homer GUELEN, Lars NEIJSSEN, Jost FU, Yali GIESEKE, Friederike SCHUURMAN, Janine BREIJ, Esther Cornelia Wilhelmina |
| description | The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. |
| format | Patent |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER |
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