HUMAN FIBROBLAST GROWTH FACTOR 1 (FGF-1) MUTEINS, THEIR DIMERS AND USES

The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.

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Bibliographische Detailangaben
Hauptverfasser:	ZAKRZEWSKA, Małgorzata Urszula, DRZAZGA, Ewa, BUDA, Paweł, CZYREK, Aleksandra Anna, KROWARSCH, Daniel Rafał, PIECZYKOLAN, Jerzy Szczepan, BAZYDŁO-GUZENDA, Katarzyna, WIECZOREK, Maciej, OTLEWSKI, Jacek Józef, JANISZEWSKI, Michał Mieczysław
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.