MULTIPLEX METHODS OF DETECTING MOLECULES USING NANOPORES
A method for detecting multiple molecules in a sample, the method comprising: (a) contacting the sample with a carrier and a nanopore, wherein the carrier comprises a single-stranded leader, an identifier region and a molecule-binding region specific for a molecule to be detected, and wherein a moto...
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| creator | EDEL, Joshua IVANOV, Aleksandar KOCH, Caroline HERON, Andrew John XUE, Liang GUTIERREZ, Richard Alexander REILLY-O'DONNELL, Benedict |
| description | A method for detecting multiple molecules in a sample, the method comprising: (a) contacting the sample with a carrier and a nanopore, wherein the carrier comprises a single-stranded leader, an identifier region and a molecule-binding region specific for a molecule to be detected, and wherein a motor protein is bound to the carrier such that it can control the movement of the identifier region within the nanopore; (b) taking one or more optical or electrical measurements as a carrier moves within the nanopore to characterise the identifier region and to determine whether or not the molecule is bound to the molecule-binding region. |
| format | Patent |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | MULTIPLEX METHODS OF DETECTING MOLECULES USING NANOPORES |
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