TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO- N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2- YLJ-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME

TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO- N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2- YLJ-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME

The present disclosure provides a novel palatable pharmaceutical composition in the form of taste-masked 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and orally disintegrating tablets comprising the same. The taste-masked orally disintegrating tablets of th...

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Hauptverfasser: BUTTERBAUGH, Adam Shane, TERNIK, Robert Louis, ALLGEIER, Matthew Carl
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator BUTTERBAUGH, Adam Shane
TERNIK, Robert Louis
ALLGEIER, Matthew Carl
description The present disclosure provides a novel palatable pharmaceutical composition in the form of taste-masked 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and orally disintegrating tablets comprising the same. The taste-masked orally disintegrating tablets of this invention will significantly reduce the potently bitter taste of lasmiditan, and enable administration of this product form to migraine patients, in particular pediatric patients and those suffering from nausea due to migraine attacks.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO- N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2- YLJ-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME
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