VON WILLEBRAND FACTOR (VWF) INHIBITORS
The invention relates to inhibitors of Von Willebrand Factor (VWF), and particularly to anti-VWF antibodies. The invention extends to compositions comprising the inhibitors, including pharmaceutical compositions and kits. The invention also extends to methods of making and using the inhibitors, for...
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Zusammenfassung: | The invention relates to inhibitors of Von Willebrand Factor (VWF), and particularly to anti-VWF antibodies. The invention extends to compositions comprising the inhibitors, including pharmaceutical compositions and kits. The invention also extends to methods of making and using the inhibitors, for example in therapy and diagnosis of conditions caused by platelet-mediated aggregation, including various cardiovascular diseases, such as acquired thrombotic thrombocytopenia purpura (aTTP), ischemic stroke and atherosclerosis. |
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