VIRAL TARGETING OF HEMATOPOIETIC STEM CELLS

Disclosed herein are compositions of retroviruses and methods of using the same for gene delivery to a hematopoietic stem cell (HSC), wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non- viral membrane -bound protein...

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Hauptverfasser: BURNETT, Cassandra, BIRNBAUM, Michael, DOBSON, Connor, GAGLIONE, Stephanie, ROYBAL, Kole
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creator BURNETT, Cassandra
BIRNBAUM, Michael
DOBSON, Connor
GAGLIONE, Stephanie
ROYBAL, Kole
description Disclosed herein are compositions of retroviruses and methods of using the same for gene delivery to a hematopoietic stem cell (HSC), wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non- viral membrane -bound protein comprising a membrane-bound domain and an extracellular targeting domain.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title VIRAL TARGETING OF HEMATOPOIETIC STEM CELLS
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