SINGLE HIGH DOSE OF MVA INDUCES A PROTECTIVE IMMUNE RESPONSE IN NEONATES AND INFANTS

The invention relates to compositions and methods for inducing a protective immune response against a poxvirus in a human neonate or infant of less than 6 months of age. The invention encompasses administering a single high dose of an MVA to a human neonate or infant of less than 6 months of age, wh...

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Bibliographische Detailangaben
Hauptverfasser: Volkmann, Ariane, Cheminay, Cédric, Suter, Mark, Chaplin, Paul
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compositions and methods for inducing a protective immune response against a poxvirus in a human neonate or infant of less than 6 months of age. The invention encompasses administering a single high dose of an MVA to a human neonate or infant of less than 6 months of age, wherein the administration induces protective T- and B cell responses against a poxvirus in the human neonate or infant.