SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES

The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase.

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Hauptverfasser: KHOSSRAVI, Mehrnaz, ROY, Amit, BELLO, Akintunde, ZHAO, Xiaochen, HART, Scott, VEZINA, Heather, HUANG, Masano, MANTRI, Rao, SANGHAVI, Kinjal, HABY, Thomas, MURTHY, Bindu, ARAS, Urvi
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creator KHOSSRAVI, Mehrnaz
ROY, Amit
BELLO, Akintunde
ZHAO, Xiaochen
HART, Scott
VEZINA, Heather
HUANG, Masano
MANTRI, Rao
SANGHAVI, Kinjal
HABY, Thomas
MURTHY, Bindu
ARAS, Urvi
description The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES
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